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Literature DB >> 15830482

In vitro resistance of Neisseria gonorrhoeae to metronidazole.

T T Yoshikawa, S Miyamoto, A W Chow, L B Guze.

Abstract

Susceptibility of 64 clinical isolates of Neisseria gonorrhoeae to metronidazole was determined by the agar dilution technique using Mueller-Hinton and chocolate agar media. All isolates were resistant to metronidazole at 12.5 mug/ml in either medium. This lack of activity of metronidazole against N. gonorrhoeae would suggest that the ability to recover N. gonorrhoeae in patients being treated with metronidazole for concurrent Trichomonas vaginalis infections should not be hampered.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1974 PMID： 15830482 PMCID： PMC444646 DOI： 10.1128/AAC.6.3.327

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

13 in total

1. [The activity of 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (R. P. 8823) against experimental Trichomonas vaginalis infections].

Authors: C COSAR; L JULOU
Journal: Ann Inst Pasteur (Paris) Date: 1959-02

2. Influence of metronidazole on treponema pallidum in vivo and in vitro.

Authors: S E Holm; H Mobacken
Journal: Acta Derm Venereol Date: 1972 Impact factor: 4.437

3. Single doses of methacycline and doxycycline for gonorrhea: a cooperative study of the frequency and cause of treatment failure.

Authors: P J Wiesner; K K Holmes; P F Sparling; M J Maness; D M Bear; L T Gutman; W W Karney
Journal: J Infect Dis Date: 1973-04 Impact factor: 5.226

1. Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance.

Authors: Gil M Penuliar; Kumiko Nakada-Tsukui; Tomoyoshi Nozaki
Journal: Front Microbiol Date: 2015-05-05 Impact factor: 5.640

1 in total

In vitro resistance of Neisseria gonorrhoeae to metronidazole.

1. [The activity of 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (R. P. 8823) against experimental Trichomonas vaginalis infections].

2. Influence of metronidazole on treponema pallidum in vivo and in vitro.

3. Single doses of methacycline and doxycycline for gonorrhea: a cooperative study of the frequency and cause of treatment failure.

4. In vitro susceptibility of oral spirochetes to metronidazole.

5. Effect of metronidazole on hydrogen production by Clostridium acetobutylicum.

6. Bactericidal activity of five antimicrobial agents against Bacteroides fragilis.

7. Tinidazole and metronidazole pharmocokinetics in man and mouse.

8. The mode of action of metronidazole against Trichomonas vaginalis.

9. Metronidazole in human infections with syphilis.

10. Metronidazole versus anaerobes. In vitro data and initial clinical observations.

1. Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance.