Literature DB >> 15830467

Speed of bactericidal action of penicillin G, ampicillin, and carbenicillin on Bacteroides fragilis.

E Schoutens, E Yourassowsky.   

Abstract

In order to determine the therapeutic value of penicillins in the management of anaerobic infections caused by Bacteroides fragilis, the antibacterial activity of penicillin G, ampicillin, and carbenicillin against 10 strains of B. fragilis subsp. fragilis, isolated from clinical material, was studied. This was undertaken by using a triple-layer technique, enzymatic inactivation of the antibiotics, and an automatic colony counter, which allowed a quantitative and a qualitative approach to the problem. Results indicated in vitro bactericidal activity with 40 mug of penicillin G, ampicillin, and carbenicillin per ml against all strains tested. However, carbenicillin had the most rapid activity.

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Year:  1974        PMID： 15830467      PMCID： PMC444631          DOI： 10.1128/AAC.6.3.227

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  [GRAM-NEGATIVE NONSPORULATED ANAEROBIC BACILLI PROMOTED BY BILE. THEIR PLACE IN THE EGGERTHELLA GENUS (N. GEN.)].

Authors:  H BEERENS; Y SCHAFFNER; J GUILLAUME; M M CASTEL
Journal:  Ann Inst Pasteur Lille       Date:  1963

2.  The susceptibility of Bacteroides fragilis to 24 antibiotics.

Authors:  J W Kislak
Journal:  J Infect Dis       Date:  1972-03       Impact factor: 5.226

3.  [Empyema of the pleura caused by the anerobe, non-spore-producing bacteria species Sphaerophorus necrophorus].

Authors:  H Werner; H Hussels; F Neuhaus
Journal:  Dtsch Med Wochenschr       Date:  1971-01-29       Impact factor: 0.628

4.  Endocarditis due to anaerobic gram-negative bacilli.

Authors:  L J Nastro; S M Finegold
Journal:  Am J Med       Date:  1973-04       Impact factor: 4.965

5.  Anaerobic bacteremia.

Authors:  W R Wilson; W J Martin; C J Wilkowske; J A Washington
Journal:  Mayo Clin Proc       Date:  1972-09       Impact factor: 7.616

6.  Bactericidal activity of five antimicrobial agents against Bacteroides fragilis.

Authors:  L J Nastro; S M Finegold
Journal:  J Infect Dis       Date:  1972-07       Impact factor: 5.226

7.  [Strains of Eggerthella from pathological material and from stool specimen].

Authors:  H Werner
Journal:  Arch Hyg Bakteriol       Date:  1967-10

8.  Antibiotic disc susceptibility tests for rapid presumptive identification of Gram-negative anaerobic bacilli.

Authors:  V L Sutter; S M Finegold
Journal:  Appl Microbiol       Date:  1971-01

9.  Standardized antimicrobial disc susceptibility testing of anaerobic bacteria. I. Susceptibility of Bacteroides fragilis to tetracycline.

Authors:  V L Sutter; Y Y Kwok; S M Finegold
Journal:  Appl Microbiol       Date:  1972-02

10.  Treatment of severe bacteroides infections with parenteral clindamycin.

Authors:  E V Haldane; C E Van Rooyen
Journal:  Can Med Assoc J       Date:  1972-12-23       Impact factor: 8.262
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  8 in total

1.  A simple test to demonstrate antibiotic synergism.

Authors:  E Yourassowsky; M P Vanderlinden; E Schoutens
Journal:  J Clin Pathol       Date:  1975-12       Impact factor: 3.411

2.  Paradoxical action of penicillin G on Staphylococcus aureus: a time study of the effect of a zonal antibiotic concentration gradient on bacterial growth.

Authors:  E Yourassowsky; M P Vanderlinden; M J Lismont; E Schoutens
Journal:  Antimicrob Agents Chemother       Date:  1975-09       Impact factor: 5.191

3.  Susceptibility to beta-lactam antibiotics and production of beta-lactamase in Bacteroides fragilis.

Authors:  B Olsson; K Dornbusch; C E Nord
Journal:  Med Microbiol Immunol       Date:  1977-10-07       Impact factor: 3.402

4.  Diagnosis and thereapy of necrotizing soft tissue infections of the perineum.

Authors:  P H Rosenberg; J M Shuck; B D Tempest; W P Reed
Journal:  Ann Surg       Date:  1978-04       Impact factor: 12.969

5.  Unique bactericidal action of metronidazole against Bacteroides fragilis and Clostridium perfringens.

Authors:  E D Ralph; W M Kirby
Journal:  Antimicrob Agents Chemother       Date:  1975-10       Impact factor: 5.191

6.  Comparative growth rates of selected anaerobic species in four commonly used broth media.

Authors:  W Sottile; R J Zabransky
Journal:  Antimicrob Agents Chemother       Date:  1977-03       Impact factor: 5.191

7.  Identification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC from the Skin Secretion of the Red-Eyed Tree Frog Agalychnis callidryas.

Authors:  Zijian Gong; Xinjie Pei; Shen Ren; Xiaoling Chen; Lei Wang; Chengbang Ma; Xinping Xi; Tianbao Chen; Chris Shaw; Mei Zhou
Journal:  Antibiotics (Basel)       Date:  2020-05-10

8.  Exploration of the Structure-Function Relationships of a Novel Frog Skin Secretion-Derived Bioactive Peptide, t-DPH1, through Use of Rational Design, Cationicity Enhancement and In Vitro Studies.

Authors:  Haixin Qin; Hantian Fang; Xiaoling Chen; Lei Wang; Chengbang Ma; Xinping Xi; Tianbao Chen; Chris Shaw; Mei Zhou
Journal:  Antibiotics (Basel)       Date:  2021-12-14
  8 in total

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