Literature DB >> 15827272

Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever.

Thanh Hung Nguyen1, Trong Lan Nguyen, Huan-Yao Lei, Yee-Shin Lin, Bich Lien Le, Kao-Jean Huang, Chiou-Feng Lin, Quang Ha Do, Thi Que Huong Vu, Thi My Lam, Trai-Ming Yeh, Jyh-Hsiung Huang, Ching-Chuan Liu, Scott B Halstead.   

Abstract

The association between sex, nutritional status, and the severity of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), and immune status was investigated in 245 Vietnamese infants with predominantly primary infections with dengue virus. Male and female infants were at equal risk of developing DHF/DSS. However, infants of low height and weight for age were under-represented among DHF/DSS cases compared with 533 healthy baby clinic infant controls. Acute illness phase blood levels of selected cytokines (interferon-gamma and tumor necrosis factor-alpha) and serum levels of antibodies to dengue virus were elevated in the same range in male and female infants with DHF/DSS, as well as in infants with and without malnutrition.

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Year:  2005        PMID： 15827272

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  31 in total

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8.  Maternal antibody and viral factors in the pathogenesis of dengue virus in infants.

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