| Literature DB >> 15826828 |
Abstract
It has become clear that the regulation of T cell numbers is under peripheral homeostatic control. However, the rules for homeostasis vary with the T cells' differentiation state and the overall T cell number in the animal. Furthermore, homeostatic pressures can cause unexpected changes in T cell differentiation and function which might promote or dampen T cell reactivity. In this review, we focus on the role of peptide/MHC and cytokine interactions in regulating the size and composition of the T cell pool.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15826828 DOI： 10.1016/j.smim.2005.02.003
Source DB: PubMed Journal: Semin Immunol ISSN： 1044-5323 Impact factor: 11.130