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Literature DB >> 15825407

Synergy between cephalosporin and aminoglycoside antibiotics against Providencia and Proteus.

Abstract

Clinical isolates of Providencia and Proteus with relative aminoglycoside resistance were tested for susceptibility to combinations of gentamicin or tobramycin with cephalothin or cefazolin. The minimal bactericidal concentration of aminoglycoside for one-third of the strains was reduced by fourfold or more in the presence of one-fourth of the minimal bactericidal concentration of either cephalosporin. This effect was achieved by clinically attainable concentrations of cephalothin or cefazolin.

Entities: Chemical

Mesh：

Substances：

Year: 1974 PMID： 15825407 PMCID： PMC429016 DOI： 10.1128/AAC.5.6.571

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

17 in total

1. Acute renal failure after high doses of gentamicin and cephalothin.

Authors: D Kleinknecht; D Ganeval; D Droz
Journal: Lancet Date: 1973-05-19 Impact factor: 79.321

2. Cephalothin, gentamicin, colistin hazards.

Authors: P D Hansten
Journal: JAMA Date: 1973-03-05 Impact factor: 56.272

3. Providencia stuartii sepsis: a new challenge in the treatment of thermal injury.

Authors: P W Curreri; H M Bruck; R B Lindberg; A D Mason; B A Pruitt
Journal: Ann Surg Date: 1973-02 Impact factor: 12.969

4. Nebulizer contamination in a burn unit.

Authors: A H Morris
Journal: Am Rev Respir Dis Date: 1973-05

5. Anuria and acute tubular necrosis associated with gentamicin and cephalothin.

Authors: S N Bobrow; E Jaffe; R C Young
Journal: JAMA Date: 1972-12-18 Impact factor: 56.272

6. Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety.

Authors: M Brzezinska; R Benveniste; J Davies; P J Daniels; J Weinstein
Journal: Biochemistry Date: 1972-02-29 Impact factor: 3.162

Synergy between cephalosporin and aminoglycoside antibiotics against Providencia and Proteus.

1. Acute renal failure after high doses of gentamicin and cephalothin.

2. Cephalothin, gentamicin, colistin hazards.

3. Providencia stuartii sepsis: a new challenge in the treatment of thermal injury.

4. Nebulizer contamination in a burn unit.

5. Anuria and acute tubular necrosis associated with gentamicin and cephalothin.

6. Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety.

7. Antimicrobial activity of the carbenicillin-gentamicin combination against gram-negative bacilli.

8. Bacteriological and clinical activity of the ampicillin-gentamicin and cephalothin-gentamicin combinations.

9. Acute renal failure associated with combined gentamicin and cephalothin therapy.

10. In vitro effects of carbenicillin combined with gentamicin or polymyxin B against Pseudomonas aeruginosa.

Review 1. Tobramycin: a review of its antibacterial and pharmacokinetic properties and therapeutic use.

2. Synergy of mecillinam, a beta-amidinopenicillanic acid derivative, combined with beta-lactam antibiotics.