Literature DB >> 15824653

Long-term posttraumatic stress disorder persists after major trauma in adolescents: new data on risk factors and functional outcome.

Troy L Holbrook1, David B Hoyt, Raul Coimbra, Bruce Potenza, Michael Sise, John P Anderson.   

Abstract

BACKGROUND: Little is known about long-term psychological outcomes after major trauma in adolescents, a leading cause of death and preventable morbidity in this age group. A prospective epidemiologic study was conducted to examine quality of life (QoL) and posttraumatic stress disorder (PTSD) outcomes in injured adolescents. The specific objectives of the present report are to describe long-term PTSD and to identify risk factors for long-term PTSD and the impact of PTSD on QoL.
METHODS: Between April 26, 1999, and November 13, 2002, 401 eligible trauma patients aged 12 to 19 years triaged to five participating trauma center hospitals in a regionalized trauma system were enrolled in the study. The admission criteria for patients were as follows: age 12 to 19 years and injury diagnoses excluding severe traumatic brain injury or spinal cord injury. PTSD was diagnosed with the Impact of Events Scale-Revised; scores of 24+ were used to diagnose PTSD. QoL after trauma was measured using the Quality of Well-Being scale, a sensitive and well-validated functional index (range: 0 = death to 1.000 = optimum functioning). Patient outcomes were assessed at discharge and at 3, 6, 12, 18, and 24 months after discharge.
RESULTS: The rate of long-term PTSD was 27%, with high rates over the follow-up period. Risk factors for long-term PTSD were perceived threat to life (odds ratio [OR], 2.2; p < 0.001.); death of a family member at the scene (OR, 4.7; p < 0.001); no control over injury event (OR, 1.7; p < 0.05), and violence-related injury (OR, 2.2; p < 0.05). PTSD in adolescents was significantly and strongly associated with female gender, older age, low socioeconomic status, drug and alcohol abuse, and other adolescent behavioral problems. Long-term PTSD was also associated with marked and significant QoL deficits throughout the 24-month follow-up interval.
CONCLUSION: High rates of long-term PTSD persist after major trauma in adolescents. Injury events such as perceived threat to life and control over the event are strongly associated with PTSD risk. Prolonged PTSD severely impacts QoL outcomes. Early identification and treatment of risk factors for long-term PTSD will be important to improve outcomes in injured adolescents.

Entities:  

Mesh:

Year:  2005        PMID: 15824653     DOI: 10.1097/01.ta.0000159247.48547.7d

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  45 in total

Review 1.  Health-related quality of life in children and adolescents following traumatic injury: a review.

Authors:  Susanne P Martin-Herz; Douglas F Zatzick; Robert J McMahon
Journal:  Clin Child Fam Psychol Rev       Date:  2012-09

Review 2.  [Sequelae of severe injuries : consequences for trauma rehabilitation].

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Journal:  Chirurg       Date:  2013-09       Impact factor: 0.955

3.  Systematic, theoretically-grounded development and feasibility testing of an innovative, preventive web-based game for children exposed to acute trauma.

Authors:  Meghan L Marsac; Flaura K Winston; Aimee K Hildenbrand; Kristen L Kohser; Sonja March; Justin Kenardy; Nancy Kassam-Adams
Journal:  Clin Pract Pediatr Psychol       Date:  2015

4.  Prospective risk factors for adolescent PTSD: sources of differential exposure and differential vulnerability.

Authors:  Stephanie Milan; Kate Zona; Jenna Acker; Viana Turcios-Cotto
Journal:  J Abnorm Child Psychol       Date:  2013-02

5.  Numbers of Severely Injured Patients in Germany. A Retrospective Analysis From the DGU (German Society for Trauma Surgery) Trauma Registry.

Authors:  Florian Debus; Rolf Lefering; Michael Frink; Christian Alexander Kühne; Carsten Mand; Benjamin Bücking; Steffen Ruchholtz
Journal:  Dtsch Arztebl Int       Date:  2015-12-04       Impact factor: 5.594

Review 6.  Traumatic brain injury induced hypothalamic-pituitary dysfunction: a paediatric perspective.

Authors:  Carlo L Acerini; Robert C Tasker
Journal:  Pituitary       Date:  2007       Impact factor: 4.107

7.  A randomized stepped care intervention trial targeting posttraumatic stress disorder for surgically hospitalized injury survivors.

Authors:  Douglas Zatzick; Gregory Jurkovich; Frederick P Rivara; Joan Russo; Amy Wagner; Jin Wang; Chris Dunn; Sarah Peregrine Lord; Megan Petrie; Stephen S Oʼconnor; Wayne Katon
Journal:  Ann Surg       Date:  2013-03       Impact factor: 12.969

Review 8.  Implementing a Trauma-Informed Approach in Pediatric Health Care Networks.

Authors:  Meghan L Marsac; Nancy Kassam-Adams; Aimee K Hildenbrand; Elizabeth Nicholls; Flaura K Winston; Stephen S Leff; Joel Fein
Journal:  JAMA Pediatr       Date:  2016-01       Impact factor: 16.193

9.  Pedestrian injuries: emergency care considerations.

Authors:  Bharath Chakravarthy; Shahram Lotfipour; Federico E Vaca
Journal:  Cal J Emerg Med       Date:  2007-02

10.  Burden of injury in childhood and adolescence in 8 European countries.

Authors:  Suzanne Polinder; Juanita A Haagsma; Hidde Toet; Marco J P Brugmans; Ed F van Beeck
Journal:  BMC Public Health       Date:  2010-01-29       Impact factor: 3.295

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