OBJECTIVE: Although numerous studies have reported an elevated lung cancer risk among chromium chemical production employees, few studies have focused on employees hired after major process changes and enhanced industrial hygiene controls were implemented. METHODS: This study examines the mortality experience of two post-change cohorts of chromate production employees constituting the current US chromium chemical industry. RESULTS: Mortality among chromium chemical workers generally was lower than expected on the basis of national and state-specific referent populations. Lung cancer mortality was 16% lower than expected, with only three lung cancer deaths (3.59 expected). CONCLUSION: The absence of an elevated lung cancer risk may be a favorable reflection of the post-change environment. However, longer follow-up allowing an appropriate latency for the entire cohort will be needed to confirm this conclusion.
OBJECTIVE: Although numerous studies have reported an elevated lung cancer risk among chromium chemical production employees, few studies have focused on employees hired after major process changes and enhanced industrial hygiene controls were implemented. METHODS: This study examines the mortality experience of two post-change cohorts of chromate production employees constituting the current US chromium chemical industry. RESULTS: Mortality among chromium chemical workers generally was lower than expected on the basis of national and state-specific referent populations. Lung cancer mortality was 16% lower than expected, with only three lung cancer deaths (3.59 expected). CONCLUSION: The absence of an elevated lung cancer risk may be a favorable reflection of the post-change environment. However, longer follow-up allowing an appropriate latency for the entire cohort will be needed to confirm this conclusion.
Authors: Andreas Seidler; Sabine Jähnichen; Janice Hegewald; Alba Fishta; Olga Krug; Luisa Rüter; Claudia Strik; Ernst Hallier; Sebastian Straube Journal: Int Arch Occup Environ Health Date: 2013-05-28 Impact factor: 3.015
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Authors: Chad M Thompson; Deborah M Proctor; Mina Suh; Laurie C Haws; Christopher R Kirman; Mark A Harris Journal: Crit Rev Toxicol Date: 2013-03 Impact factor: 5.635
Authors: Andrea Caglieri; Matteo Goldoni; Olga Acampa; Roberta Andreoli; Maria Vittoria Vettori; Massimo Corradi; Pietro Apostoli; Antonio Mutti Journal: Environ Health Perspect Date: 2006-04 Impact factor: 9.031