Literature DB >> 15824445

Genotype, phenotype and cancer: role of low penetrance genes and environment in tumour susceptibility.

Ashwin Kotnis1, Rajiv Sarin, Rita Mulherkar.   

Abstract

Role of heredity and lifestyle in sporadic cancers is well documented. Here we focus on the influence of low penetrance genes and habits, with emphasis on tobacco habit in causing head and neck cancers. Role of such gene-environment interaction can be well studied in individuals with multiple primary cancers. Thus such a biological model may elucidate that cancer causation is not solely due to genetic determinism but also significantly relies on lifestyle of the individual.

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Year:  2005        PMID： 15824445     DOI： 10.1007/BF02705154

Source DB:  PubMed          Journal:  J Biosci        ISSN： 0250-5991            Impact factor:   2.795


  70 in total

1.  Single-nucleotide polymorphisms in the public domain: how useful are they?

Authors:  G Marth; R Yeh; M Minton; R Donaldson; Q Li; S Duan; R Davenport; R D Miller; P Y Kwok
Journal:  Nat Genet       Date:  2001-04       Impact factor: 38.330

Review 2.  The hallmarks of cancer.

Authors:  D Hanahan; R A Weinberg
Journal:  Cell       Date:  2000-01-07       Impact factor: 41.582

3.  Gene-environment interaction and aetiology of cancer: what does it mean and how can we measure it?

Authors:  Paul Brennan
Journal:  Carcinogenesis       Date:  2002-03       Impact factor: 4.944

Review 4.  Cancer epidemiology in the last century and the next decade.

Authors:  J Peto
Journal:  Nature       Date:  2001-05-17       Impact factor: 49.962

5.  An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology.

Authors:  Yong Zhu; Margaret R Spitz; Christopher I Amos; Jie Lin; Matthew B Schabath; Xifeng Wu
Journal:  Cancer Res       Date:  2004-03-15       Impact factor: 12.701

6.  Cytochrome P4501A2 (CYP1A2) activity and lung cancer risk: a preliminary study among Chinese women in Singapore.

Authors:  A Seow; B Zhao; E J Lee; W T Poh; M Teh; P Eng; Y T Wang; W C Tan; H P Lee
Journal:  Carcinogenesis       Date:  2001-04       Impact factor: 4.944

7.  Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.

Authors:  A Risch; D M Wallace; S Bathers; E Sim
Journal:  Hum Mol Genet       Date:  1995-02       Impact factor: 6.150

8.  Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco.

Authors:  Sameer Jhavar; Rajiv Sarin; Rita Mulherkar; Axel Benner; Jai Prakash Agarwal; Ketayun Dinshaw
Journal:  Oral Oncol       Date:  2004-01       Impact factor: 5.337

9.  Second malignant neoplasia in patients with T1 glottic cancer treated with radiation.

Authors:  M Fujita; M S Rudoltz; D J Canady; P Patel; M Machtay; M Q Pittard; M Mohiuddin; W F Regine
Journal:  Laryngoscope       Date:  1998-12       Impact factor: 3.325

Review 10.  Colorectal cancer and inherited mutations in base-excision repair.

Authors:  Elizabeth Chow; Christina Thirlwell; Finlay Macrae; Lara Lipton
Journal:  Lancet Oncol       Date:  2004-10       Impact factor: 41.316
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  13 in total

1.  Distinct perturbations of oral squamous cell carcinoma patients: A quantitative cytomorphometric analysis.

Authors:  Deepti Sharma; Simarpreet V Sandhu; Himanta Bansal; Shruti Gupta
Journal:  Int J Health Sci (Qassim)       Date:  2015-07

2.  Mosquitocidal and water purification properties of Cynodon dactylon, Aloe vera, Hemidesmus indicus and Coleus amboinicus leaf extracts against the mosquito vectors.

Authors:  Nareshkumar Arjunan; Kadarkarai Murugan; Pari Madhiyazhagan; Kalimuthu Kovendan; Kanagarajan Prasannakumar; Sundaram Thangamani; Donald R Barnard
Journal:  Parasitol Res       Date:  2011-09-23       Impact factor: 2.289

Review 3.  Polymorphisms in human DNA repair genes and head and neck squamous cell carcinoma.

Authors:  Rim Khlifi; Ahmed Rebai; Amel Hamza-Chaffai
Journal:  J Genet       Date:  2012       Impact factor: 1.166

4.  Redifferentiation of human hepatoma cells (SMMC-7721) induced by two new highly oxygenated bisabolane-type sesquiterpenes.

Authors:  Ruidong Miao; Juan Wei; Qi Zhang; Venkateswara Sajja; Jinbo Yang; Qin Wang
Journal:  J Biosci       Date:  2008-12       Impact factor: 1.826

5.  Gene Polymorphisms of ADIPOQ +45T>G, UCP2 -866G>A, and FABP2 Ala54Thr on the Risk of Colorectal Cancer: A Matched Case-Control Study.

Authors:  Xiaoqin Hu; Ping Yuan; Jin Yan; Fei Feng; Xiaoling Li; Wenhui Liu; Yanfang Yang
Journal:  PLoS One       Date:  2013-06-27       Impact factor: 3.240

6.  Establishment & characterization of lymphoblastoid cell lines from patients with multiple primary neoplasms in the upper aero-digestive tract & healthy individuals.

Authors:  Tabish Hussain; Ashwin Kotnis; Rajiv Sarin; Rita Mulherkar
Journal:  Indian J Med Res       Date:  2012-06       Impact factor: 2.375

7.  Multiple pathway-based genetic variations associated with tobacco related multiple primary neoplasms.

Authors:  Ashwin Kotnis; Junghyun Namkung; Sadhana Kannan; Nallala Jayakrupakar; Taesung Park; Rajiv Sarin; Rita Mulherkar
Journal:  PLoS One       Date:  2012-01-11       Impact factor: 3.240

8.  Changes at the CYP2C locus and disruption of CYP2C8/9 linkage disequilibrium in patients with essential tremor.

Authors:  Carmen Martínez; Elena García-Martín; Hortensia Alonso-Navarro; Félix Javier Jiménez-Jiménez; Julián Benito-León; Isabel García-Ferrer; Pilar Vázquez-Torres; Inmaculada Puertas; José M Zurdo; Tomás López-Alburquerque; José A G Agúndez
Journal:  Neuromolecular Med       Date:  2007       Impact factor: 4.103

9.  Case-control study and meta-analysis of SULT1A1 Arg213His polymorphism for gene, ethnicity and environment interaction for cancer risk.

Authors:  A Kotnis; S Kannan; R Sarin; R Mulherkar
Journal:  Br J Cancer       Date:  2008-10-21       Impact factor: 7.640

10.  Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer.

Authors:  Chunhong Fan; Mingjuan Jin; Kun Chen; Yongjing Zhang; Shuangshuang Zhang; Bing Liu
Journal:  BMC Cancer       Date:  2007-06-30       Impact factor: 4.430
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