Literature DB >> 15823000

An efficient synthesis of valienamine via ring-closing metathesis.

Young-Kil Chang1, Bo-Young Lee, Dong Jun Kim, Gwan Sun Lee, Heung Bae Jeon, Kwan Soo Kim.   

Abstract

An efficient synthesis of valienamine is described. Valienamine was synthesized starting from commercially available 2,3,4,6-tetra-O-benzyl-D-glucose in nine steps, using ring-closing metathesis of (4S,5S,6S)-4,5,6-tribenzyloxy-7-(benzyloxymethyl)octa-1,7-dien-3-ol as a key step.

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Year:  2005        PMID: 15823000     DOI: 10.1021/jo047735x

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

1.  Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis.

Authors:  Jongtae Yang; Hui Xu; Yirong Zhang; Linquan Bai; Zixin Deng; Taifo Mahmud
Journal:  Org Biomol Chem       Date:  2010-10-27       Impact factor: 3.876

2.  Genetically engineered production of 1,1'-bis-valienamine and validienamycin in Streptomyces hygroscopicus and their conversion to valienamine.

Authors:  Hui Xu; Jongtae Yang; Linquan Bai; Zixin Deng; Taifo Mahmud
Journal:  Appl Microbiol Biotechnol       Date:  2008-09-27       Impact factor: 4.813

3.  Synthetic efforts for stereo structure determination of cytotoxic marine natural product pericosines as metabolites of Periconia sp. from sea hare.

Authors:  Yoshihide Usami; Hayato Ichikawa; Masao Arimoto
Journal:  Int J Mol Sci       Date:  2008-03-24       Impact factor: 6.208

  3 in total

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