| Literature DB >> 15822932 |
A Tempez1, M Ugarov, T Egan, J A Schultz, A Novikov, S Della-Negra, Y Lebeyec, M Pautrat, M Caroff, V S Smentkowski, H-Y J Wang, S N Jackson, A S Woods.
Abstract
The implantation of low velocity massive gold cluster ions allows homogeneous incorporation of a metallic matrix into the near-surface region of rat brain tissues. Subsequent analysis by laser desorption ionization mass spectrometry yields spectra exhibiting molecular ion peaks in the mass range up to 35 kDa similar to those observed by matrix-assisted LDI. Matrix-implanted LDI when combined with ion-mobility preseparation promises to be a useful technique for molecular imaging of biotissues with a laser microprobe.Entities:
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Year: 2005 PMID： 15822932 DOI： 10.1021/pr0497879
Source DB: PubMed Journal: J Proteome Res ISSN： 1535-3893 Impact factor: 4.466