Literature DB >> 1582264

Isolation of monochromosomal hybrids following fusion of human diploid fibroblast-derived microcells with mouse A9 cells.

Y Ning1, M Lovell, L Taylor, O M Pereira-Smith.   

Abstract

Rodent x human hybrids containing single human chromosomes are valuable tools in the study of human genetics. Using a retrovirus carrying the neomycin gene, we generated a neomycin-resistant (neor) pool of human diploid fibroblasts. Following fusion of microcells prepared from this pool to mouse A9 cells, we obtained four neor hybrids containing a single human chromosome 2, 3, 5, or 15.

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Year:  1992        PMID： 1582264     DOI： 10.1159/000133300

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  8 in total

1.  A model system to study genomic imprinting of human genes.

Authors:  J M Gabriel; M J Higgins; T C Gebuhr; T B Shows; S Saitoh; R D Nicholls
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

2.  Human monochromosome hybrid cell panel characterized by FISH in the JCRB/HSRRB.

Authors:  H Tanabe; Y Nakagawa; D Minegishi; K Hashimoto; N Tanaka; M Oshimura; T Sofuni; H Mizusawa
Journal:  Chromosome Res       Date:  2000       Impact factor: 5.239

3.  Multiple dispersed loci produce small cytoplasmic Alu RNA.

Authors:  R J Maraia; C T Driscoll; T Bilyeu; K Hsu; G J Darlington
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272

4.  A human Alu RNA-binding protein whose expression is associated with accumulation of small cytoplasmic Alu RNA.

Authors:  D Y Chang; B Nelson; T Bilyeu; K Hsu; G J Darlington; R J Maraia
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

5.  Replication stress induces tumor-like microdeletions in FHIT/FRA3B.

Authors:  Sandra G Durkin; Ryan L Ragland; Martin F Arlt; Jennifer G Mulle; Stephen T Warren; Thomas W Glover
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-27       Impact factor: 11.205

6.  The conserved 7SK snRNA gene localizes to human chromosome 6 by homolog exclusion probing of somatic cell hybrid RNA.

Authors:  C T Driscoll; G J Darlington; R J Maraia
Journal:  Nucleic Acids Res       Date:  1994-03-11       Impact factor: 16.971

7.  The human Y4 small cytoplasmic RNA gene is controlled by upstream elements and resides on chromosome 7 with all other hY scRNA genes.

Authors:  R J Maraia; N Sasaki-Tozawa; C T Driscoll; E D Green; G J Darlington
Journal:  Nucleic Acids Res       Date:  1994-08-11       Impact factor: 16.971

8.  Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay.

Authors:  So Hae Park; Pamela Bennett-Baker; Samreen Ahmed; Martin F Arlt; Mats Ljungman; Thomas W Glover; Thomas E Wilson
Journal:  Nucleic Acids Res       Date:  2021-07-21       Impact factor: 16.971
  8 in total

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