Literature DB >> 15820892

Characterization of amino acids using Raman spectroscopy.

Amanda L Jenkins1, Richard A Larsen, Timothy B Williams.   

Abstract

A key process in the development of new drugs is elucidation of the interaction between the drug molecule and the target protein. Such knowledge then makes it possible to make systematic structural modifications of the drug molecule to optimize the interaction. Many analytical techniques can be applied to proteins in solution such as circular dichroism, ultraviolet, and fluorescence spectroscopy but these all have limitations. In this paper, we investigate the feasibility of using relatively simple, visible light Raman spectroscopic methods to investigate amino acids and related biopolymers.

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Year:  2005        PMID: 15820892     DOI: 10.1016/j.saa.2004.11.055

Source DB:  PubMed          Journal:  Spectrochim Acta A Mol Biomol Spectrosc        ISSN: 1386-1425            Impact factor:   4.098


  9 in total

1.  Temperature-sensitive gating of hCx26: high-resolution Raman spectroscopy sheds light on conformational changes.

Authors:  Ann-Kathrin Kniggendorf; Merve Meinhardt-Wollweber; Xiaogang Yuan; Bernhard Roth; Astrid Seifert; Niels Fertig; Carsten Zeilinger
Journal:  Biomed Opt Express       Date:  2014-06-06       Impact factor: 3.732

2.  Location of PRODAN in lipid layer of HDL particle: a Raman study.

Authors:  D Krilov; M Balarin; M Kosović; J Brnjas-Kraljević
Journal:  Eur Biophys J       Date:  2008-02-07       Impact factor: 1.733

3.  Application of Raman spectroscopy in type 2 diabetes screening in blood using leucine and isoleucine amino-acids as biomarkers and in comparative anti-diabetic drugs efficacy studies.

Authors:  Zephania Birech; Peter Waweru Mwangi; Fredrick Bukachi; Keith Makori Mandela
Journal:  PLoS One       Date:  2017-09-19       Impact factor: 3.240

Review 4.  Vibrational Spectroscopy Fingerprinting in Medicine: from Molecular to Clinical Practice.

Authors:  Vera Balan; Cosmin-Teodor Mihai; Florina-Daniela Cojocaru; Cristina-Mariana Uritu; Gianina Dodi; Doru Botezat; Ioannis Gardikiotis
Journal:  Materials (Basel)       Date:  2019-09-06       Impact factor: 3.623

5.  Detection of Glutamate Encapsulated in Liposomes by Optical Trapping Raman Spectroscopy.

Authors:  Kyoko Masui; Yasunori Nawa; Shunsuke Tokumitsu; Takahiro Nagano; Makoto Kawarai; Hirokazu Tanaka; Tatsuki Hamamoto; Wataru Minoshima; Tomomi Tani; Satoshi Fujita; Hidekazu Ishitobi; Chie Hosokawa; Yasushi Inouye
Journal:  ACS Omega       Date:  2022-02-28

6.  Low-cost electrochemical detection of l-tyrosine using an rGO-Cu modified pencil graphite electrode and its surface orientation on a Ag electrode using an ex situ spectroelectrochemical method.

Authors:  C Kavitha; K Bramhaiah; Neena S John
Journal:  RSC Adv       Date:  2020-06-16       Impact factor: 3.361

7.  Whey Protein Powder Analysis by Mid-Infrared Spectroscopy.

Authors:  Rose Saxton; Owen M McDougal
Journal:  Foods       Date:  2021-05-10

8.  Polythiophene synthesis coupled to quartz crystal microbalance and Raman spectroscopy for detecting bacteria.

Authors:  R P Kengne-Momo; F Lagarde; Ph Daniel; J F Pilard; M J Durand; G Thouand
Journal:  Biointerphases       Date:  2012-11-06       Impact factor: 2.456

9.  Defining Multiple Characteristic Raman Bands of α-Amino Acids as Biomarkers for Planetary Missions Using a Statistical Method.

Authors:  S M Rolfe; M R Patel; I Gilmour; K Olsson-Francis; T J Ringrose
Journal:  Orig Life Evol Biosph       Date:  2016-01-07       Impact factor: 1.950

  9 in total

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