Literature DB >> 15820161

Effect of gender on treatment, resource utilization, and outcomes in congestive heart failure in Quebec, Canada.

Richard Sheppard1, Hassan Behlouli, Hugues Richard, Louise Pilote.   

Abstract

This study assessed whether a gender gap exists in therapy, procedure use, and outcomes in patients who have a new diagnosis of congestive heart failure (CHF) at the population level. The Quebec hospital discharge database was linked with the physician and drug claims databases to identify a cohort of patients who had a diagnosis of CHF (code 428 in the International Classification of Diseases, Ninth Revision) between January 1998 and December 2002. There were 16,017 men and 16,622 women. Women who had CHF were older (78 +/- 11 vs 73 +/- 11 years, p <0.001), had more hypertension (41% vs 28%, p <0.001) and hyperlipidemia (18% vs 14%, p <0.001) but less frequent myocardial infarction (19% vs 25%, p <0.001). Women were less likely to see a cardiologist (30% vs 34%, p <0.001) and required a longer hospital stay (12.0 +/- 14.8 vs 10.6 +/- 13.3 days, p <0.001). During the first year after a first CHF hospitalization, women were less like to have an assessment of left ventricular function (61% vs 65%, p <0.001), diagnostic cardiac catheterization (11% vs 15%, p <0.001), and revascularization procedure (4% vs 6%, p <0.001). Women were less likely to be prescribed an angiotensin-converting enzyme inhibitor (60% vs 66%) and more likely to be prescribed a beta blocker (38% vs 34%). Women and men had similar yearly numbers of rehospitalizations for CHF (1.4 +/- 1.0 vs 1.5 +/- 1.0) and emergency room visits (1.7 +/- 1.2 vs 1.8 +/- 1.3). The adjusted risk of death was minimally higher in men than in women (hazard ratio 1.06, 95% confidence interval 1.03 to 1.1, p <0.01). Thus, despite less frequent cardiologist assessment, fewer cardiac-related procedures, and less frequent use of standard medical therapy, clinical outcomes in women and men who had CHF were similar.

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Year:  2005        PMID: 15820161     DOI: 10.1016/j.amjcard.2004.12.033

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  8 in total

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Journal:  Am J Med Genet A       Date:  2013-02-26       Impact factor: 2.802

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Authors:  Heidi N Schmaltz; Danielle A Southern; Colleen J Maxwell; Merril L Knudtson; William A Ghali
Journal:  J Gen Intern Med       Date:  2008-10-02       Impact factor: 5.128

3.  Influence of gender of physicians and patients on guideline-recommended treatment of chronic heart failure in a cross-sectional study.

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Journal:  Eur J Heart Fail       Date:  2009-01-21       Impact factor: 15.534

4.  Gender differences in the etiology of heart failure: A systematic review.

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5.  Readmission rates following heart failure: a scoping review of sex and gender based considerations.

Authors:  Amy Hoang-Kim; Camilla Parpia; Cassandra Freitas; Peter C Austin; Heather J Ross; Harindra C Wijeysundera; Karen Tu; Susanna Mak; Michael E Farkouh; Louise Y Sun; Michael J Schull; Robin Mason; Douglas S Lee; Paula A Rochon
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Journal:  Syst Rev       Date:  2013-01-18

Review 7.  Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis.

Authors:  Dipak Kotecha; Luis Manzano; Henry Krum; Giuseppe Rosano; Jane Holmes; Douglas G Altman; Peter D Collins; Milton Packer; John Wikstrand; Andrew J S Coats; John G F Cleland; Paulus Kirchhof; Thomas G von Lueder; Alan S Rigby; Bert Andersson; Gregory Y H Lip; Dirk J van Veldhuisen; Marcelo C Shibata; Hans Wedel; Michael Böhm; Marcus D Flather
Journal:  BMJ       Date:  2016-04-20

8.  Gender Differences in Surgery for Work-Related Musculoskeletal Injury: A Population-Based Cohort Study.

Authors:  Andrea M Jones; Mieke Koehoorn; Christopher B Mcleod
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  8 in total

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