Literature DB >> 15818184

Pneumonia in the elderly (geriatric) population.

Jean-Paul Janssens1.   

Abstract

PURPOSE OF REVIEW: Review of recent studies (2003 and 2004) concerning pneumonia in the very old. RECENT
FINDINGS: Hospitalisation for community-acquired pneumonia (CAP) in the elderly is associated with a high mortality and with a high rate of readmission within the following year. Functional status, altered mental status, number of comorbidities, aspiration pneumonia, renal failure, and nutritional status are all indicators of adverse prognosis. Although Streptococcus pneumoniae, Haemophilus influenzae, Enterobacteriacae, and Staphylococcus aureus are the most frequently identified causative microorganisms, viruses account for up to 26% of hospital admissions for CAP. Chlamydia pneumoniae is also implicated in CAP and in nursing-home-acquired pneumonia (NHAP), with recent reports of outbreaks in nursing homes. Aspiration pneumonia is frequent in the elderly and occurs with increased frequency in patients with nasogastric tubes or percutaneous enterogastric tubes. In severe aspiration pneumonia, 20% of organisms implicated are anaerobic and 80% aerobic, most of which are gram-negative Enterobacteriaceae. Poor oral hygiene increases subsequent risk of pneumonia: dental plaque may act as a reservoir for pathogenic organisms implicated in CAP or NHAP. Prevention of CAP and NHAP relies on the combined use of influenza and pneumococcal vaccination, which decreases hospital admissions and in-hospital mortality for CAP.
SUMMARY: Recent studies stress the importance of aspiration as a frequent mechanism of CAP, provide new insights as to causative organisms in this setting, and underline the contribution of combined vaccination in reducing morbidity and mortality.

Entities:  

Mesh:

Year:  2005        PMID: 15818184     DOI: 10.1097/01.mcp.0000158254.90483.1f

Source DB:  PubMed          Journal:  Curr Opin Pulm Med        ISSN: 1070-5287            Impact factor:   3.155


  29 in total

1.  Dysregulated inflammation as a risk factor for pneumonia in the elderly.

Authors:  Angela R Boyd; Carlos J Orihuela
Journal:  Aging Dis       Date:  2011-12       Impact factor: 6.745

2.  The multidimensional prognostic index predicts short- and long-term mortality in hospitalized geriatric patients with pneumonia.

Authors:  Alberto Pilotto; Filomena Addante; Luigi Ferrucci; Gioacchino Leandro; Grazia D'Onofrio; Michele Corritore; Valeria Niro; Carlo Scarcelli; Bruno Dallapiccola; Marilisa Franceschi
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2009-04-06       Impact factor: 6.053

3.  Pneumonia prevention in the elderly patients: the other sides.

Authors:  Najla Chebib; Clémence Cuvelier; Astrid Malézieux-Picard; Thibault Parent; Xavier Roux; Thomas Fassier; Frauke Müller; Virginie Prendki
Journal:  Aging Clin Exp Res       Date:  2019-12-31       Impact factor: 3.636

4.  Population-Based Assessment of Complications Following Surgery for Thyroid Cancer.

Authors:  Maria Papaleontiou; David T Hughes; Cui Guo; Mousumi Banerjee; Megan R Haymart
Journal:  J Clin Endocrinol Metab       Date:  2017-07-01       Impact factor: 5.958

Review 5.  Recurrent pneumonia: a review with focus on clinical epidemiology and modifiable risk factors in elderly patients.

Authors:  T T Dang; S R Majumdar; T J Marrie; D T Eurich
Journal:  Drugs Aging       Date:  2015-01       Impact factor: 3.923

6.  Importance of TLR2 in early innate immune response to acute pulmonary infection with Porphyromonas gingivalis in mice.

Authors:  George Hajishengallis; Min Wang; Gregory J Bagby; Steve Nelson
Journal:  J Immunol       Date:  2008-09-15       Impact factor: 5.422

7.  Gaps in patient care practices to prevent hospital-acquired delirium.

Authors:  Kannayiram Alagiakrishnan; Thomas Marrie; Darryl Rolfson; William Coke; Richard Camicioli; D'Arcy Duggan; Bonnie Launhardt; Bruce Fisher; Debbie Gordon; Marilou Hervas-Malo; Bernice Magee; Cheryl Wiens
Journal:  Can Fam Physician       Date:  2009-10       Impact factor: 3.275

8.  A cross-sectional study to investigate pneumococcal vaccination in the elderly in a low income county: patient knowledge, awareness, and attitudes of vaccination and prevalence rates by socioeconomic status.

Authors:  Shoukat Ali Baig; Maroof Hassan; Syed Mustajab Ahmed; Wardah Moazzam; Ailya Inayat
Journal:  Hum Vaccin Immunother       Date:  2014-02-04       Impact factor: 3.452

9.  Prognosis of primary care patients aged 80 years and older with lower respiratory tract infection.

Authors:  Christiana van de Nadort; Hugo M Smeets; Jettie Bont; N Peter A Zuithoff; Eelko Hak; Theo J M Verheij
Journal:  Br J Gen Pract       Date:  2009-04       Impact factor: 5.386

10.  Age-associated inflammation and toll-like receptor dysfunction prime the lungs for pneumococcal pneumonia.

Authors:  Ernesto Hinojosa; Angela R Boyd; Carlos J Orihuela
Journal:  J Infect Dis       Date:  2009-08-15       Impact factor: 5.226

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