Literature DB >> 15816725

Enantioselective H-atom transfer reaction: a strategy to synthesize formaldehyde aldol products.

Mukund P Sibi1, Kalyani Patil.   

Abstract

[reaction: see text] Enantioselective radical alkylation of Baylis-Hillman adducts furnished aldol products in good yield and selectivity. The results illustrate that the selectivity in the hydrogen atom transfer is dependent on the size of the ester substituent, with smaller substituents providing better enantioselectivity.

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Year:  2005        PMID: 15816725     DOI: 10.1021/ol047347h

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Pyrones to pyrans: enantioselective radical additions to acyloxy pyrones.

Authors:  Mukund P Sibi; Jake Zimmerman
Journal:  J Am Chem Soc       Date:  2006-10-18       Impact factor: 15.419

2.  Photoenzymatic Generation of Unstabilized Alkyl Radicals: An Asymmetric Reductive Cyclization.

Authors:  Phillip D Clayman; Todd K Hyster
Journal:  J Am Chem Soc       Date:  2020-09-03       Impact factor: 15.419

Review 3.  Conjugate addition-enantioselective protonation reactions.

Authors:  James P Phelan; Jonathan A Ellman
Journal:  Beilstein J Org Chem       Date:  2016-06-15       Impact factor: 2.883

  3 in total

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