| Literature DB >> 15816174 |
Rob D Coalson1, Maria G Kurnikova.
Abstract
The Poisson-Nernst-Planck (PNP) theory of electro-diffusion is reviewed. Techniques for numerical solution of the three-dimensional PNP equations are summarized, and several illustrative applications to ion transport through protein channels are presented. Strengths and weaknesses of the theory are discussed, as well as attempts to improve it via increasingly realistic evaluation of the force acting on each ion due to the protein/membrane environment.Mesh:
Substances:
Year: 2005 PMID: 15816174 DOI: 10.1109/tnb.2004.842495
Source DB: PubMed Journal: IEEE Trans Nanobioscience ISSN: 1536-1241 Impact factor: 2.935