| Literature DB >> 15813374 |
Ivanka Tsacheva1, Joerg Rostan, Tania Iossifova, Bernhard Vogler, Mariela Odjakova, Hernan Navas, Ivanka Kostova, Michaela Kojouharova, Wolfgang Kraus.
Abstract
The latex of Croton draco, its extracts and several latex components have been investigated for their influence on both classical (CP) and alternative (AP) activation pathways of the complement system using a hemolytic assay. The best inhibition was found for the classical pathway. The latex, ethyl acetate and ethyl ether extracts exhibited extremely high inhibition on the CP (94, 90 and 77%, respectively) at a concentration of 1 mg/ml. The flavonoid myricitrin, the alkaloid taspine and the cyclopeptides P1 and P2 showed high inhibition on CP (83, 91, 78 and 63%, respectively) at a concentration of 0.9 mM.Entities:
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Year: 2004 PMID： 15813374 DOI： 10.1515/znc-2004-7-814
Source DB: PubMed Journal: Z Naturforsch C J Biosci ISSN： 0341-0382