| Literature DB >> 15813185 |
Kazuro Shiomi1, Kenji Hatae, Hiroko Hatano, Atsuko Matsumoto, Yoko Takahashi, Cheng-Lin Jiang, Hiroshi Tomoda, Susumu Kobayashi, Haruo Tanaka, Satoshi Omura.
Abstract
A new antimycin group antibiotic, antimycin A9, was isolated from a cultured broth of Streptomyces sp. K01-0031 together with antimycins A3a, A3b, A4, and A7, and flazin methyl ester. Antimycin A9 is the first antimycin having an aromatic 8-acyl residue. It showed potent nematocidal and insecticidal activities against Caenorhabditis elegans and Artemia salina, respectively. It inhibited bovine heart NADH oxidase at nanomolar level like other known antimycins.Entities:
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Year: 2005 PMID： 15813185 DOI： 10.1038/ja.2005.10
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649