OBJECTIVES: This study investigated whether an infant diet is associated with the development of type 1 diabetes. METHODS: A case-control study was conducted in Belgrade from 1994 to 1997. A total of 105 patients with recent onset diabetes (< or = 16 y old) were compared with 210 controls chosen among children with skin disease (first control group). Cases and controls were individually matched by age (+/-1 y), sex, and place of residence. Eighty-six children with diabetes were also compared with their siblings (second control group). RESULTS: According to univariate logistic regression analysis, when cases were compared with the first control group, the risk of type 1 diabetes was greater for children who were breast fed less than 4 mo (odds ratio = 2.09, 95% confidence interval = 1.30 to 3.36) and who received cow's milk at younger than 5 mo (odds ratio = 3.39, 95% confidence interval = 2.04 to 5.66). According to univariate analysis, when cases were compared with their relatives, only early introduction of supplementary milk was associated with a higher risk for diabetes (odds ratio = 5.75, 95% confidence interval = 2.91 to 11.36). After adjusting for different confounding variables, infant diet was not independently associated with diabetes. CONCLUSIONS: The results obtained do not support the hypothesis that infant diet is related to the occurrence of type 1 diabetes.
OBJECTIVES: This study investigated whether an infant diet is associated with the development of type 1 diabetes. METHODS: A case-control study was conducted in Belgrade from 1994 to 1997. A total of 105 patients with recent onset diabetes (< or = 16 y old) were compared with 210 controls chosen among children with skin disease (first control group). Cases and controls were individually matched by age (+/-1 y), sex, and place of residence. Eighty-six children with diabetes were also compared with their siblings (second control group). RESULTS: According to univariate logistic regression analysis, when cases were compared with the first control group, the risk of type 1 diabetes was greater for children who were breast fed less than 4 mo (odds ratio = 2.09, 95% confidence interval = 1.30 to 3.36) and who received cow's milk at younger than 5 mo (odds ratio = 3.39, 95% confidence interval = 2.04 to 5.66). According to univariate analysis, when cases were compared with their relatives, only early introduction of supplementary milk was associated with a higher risk for diabetes (odds ratio = 5.75, 95% confidence interval = 2.91 to 11.36). After adjusting for different confounding variables, infant diet was not independently associated with diabetes. CONCLUSIONS: The results obtained do not support the hypothesis that infant diet is related to the occurrence of type 1 diabetes.
Authors: Darcy Güngör; Perrine Nadaud; Concetta C LaPergola; Carol Dreibelbis; Yat Ping Wong; Nancy Terry; Steve A Abrams; Leila Beker; Tova Jacobovits; Kirsi M Järvinen; Laurie A Nommsen-Rivers; Kimberly O O'Brien; Emily Oken; Rafael Pérez-Escamilla; Ekhard E Ziegler; Joanne M Spahn Journal: Am J Clin Nutr Date: 2019-03-01 Impact factor: 7.045
Authors: C R Cardwell; L C Stene; G Joner; E A Davis; O Cinek; J Rosenbauer; J Ludvigsson; C Castell; J Svensson; M J Goldacre; T Waldhoer; J Polanska; S G A Gimeno; L-M Chuang; R C Parslow; E J K Wadsworth; A Chetwynd; P Pozzilli; G Brigis; B Urbonaite; S Sipetić; E Schober; C Ionescu-Tirgoviste; C E de Beaufort; D Stoyanov; K Buschard; C C Patterson Journal: Diabetologia Date: 2010-01-10 Impact factor: 10.122
Authors: Janet K Snell-Bergeon; Jennifer Smith; Fran Dong; Anna E Barón; Kathy Barriga; Jill M Norris; Marian Rewers Journal: Diabetes Care Date: 2012-10-05 Impact factor: 19.112