| Literature DB >> 15811497 |
Bea R H Van den Bergh1, Maarten Mennes, Jaap Oosterlaan, Veerle Stevens, Peter Stiers, Alfons Marcoen, Lieven Lagae.
Abstract
This study prospectively investigated the influence of antenatal maternal anxiety, measured with the State Trait Anxiety Inventory at 12-22, 23-31 and 32-40 postmenstrual weeks of pregnancy, on cognitive functioning in 57 adolescents (mean age 15 years). ANCOVAs showed effects of State anxiety at 12-22 weeks, after controlling for influences of State anxiety in later pregnancy and postnatal maternal Trait anxiety. Adolescents of high anxious pregnant women reacted impulsively in the Encoding task; they responded faster but made more errors than adolescents of low anxious women. They also scored lower on two administered WISC-R subtests. In the Stop task no differences in inhibiting ongoing responses were found between adolescents of high and low anxious pregnant women. We suspect that high maternal anxiety in the first half of pregnancy may negatively affect brain development of the fetus, reflected by impulsivity and lower WISC-R scores at 14-15 years.Entities:
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Year: 2004 PMID： 15811497 DOI： 10.1016/j.neubiorev.2004.10.010
Source DB: PubMed Journal: Neurosci Biobehav Rev ISSN： 0149-7634 Impact factor: 8.989