| Literature DB >> 15811321 |
Stéphane Genin1, Belen Brito, Timothy P Denny, Christian Boucher.
Abstract
Expression of several virulence factors in the plant pathogen bacterium Ralstonia solanacearum is controlled by a complex regulatory network, at the center of which is PhcA. We provide genetic evidence that PhcA also represses the expression of hrp genes that code for the Type III protein secretion system, a major pathogenicity determinant in this bacterium. The repression of hrp genes in complete medium is relieved in a phcA mutant and two distinct signals, a quorum-sensing signal and complex nitrogen sources, appear to trigger this PhcA-dependent repression. This control of hrp gene expression by PhcA is realized at the level of the HrpG regulatory protein.Entities:
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Year: 2005 PMID： 15811321 DOI： 10.1016/j.febslet.2005.02.058
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124