Hongjian Liu1, Xinlin Wu, Guozhen Wu. 1. Department of Chinese Medicine, the First Affiliated Hospital of Zhongshan University, Guangzhou.
Abstract
OBJECTIVE: To evaluate the clinical study of Zhuyutongmai (ZYTM) Capsule in treating senile cerebral infarction and effect on function of vascular endothelium. METHODS:Sixty-four aged patients with cerebral infarction were randomly divided into the treated group treated with ZYTM and the control group treaded with Naoluotong. The clinical effect was observed. The hemorrheologic and hemodynamic parameters, the blood levels of endothelin (ET) and nitric oxide (NO) were determined before and after treatment. RESULTS: After treatment of ZYTM, the hemorrheologic and hemodynamic parameters were all significantly improved (P < 0.01 or P < 0.05), the therapeutic effect of ZYTM was better than that of Naoluotong (P < 0.05), compared with the control group after treatment, the level of ET in the treated group were lower (P < 0.01), and level of NO were higher (P < 0.01). CONCLUSION:ZYTM has good effect in treating senile cerebral infarction.
RCT Entities:
OBJECTIVE: To evaluate the clinical study of Zhuyutongmai (ZYTM) Capsule in treating senile cerebral infarction and effect on function of vascular endothelium. METHODS: Sixty-four aged patients with cerebral infarction were randomly divided into the treated group treated with ZYTM and the control group treaded with Naoluotong. The clinical effect was observed. The hemorrheologic and hemodynamic parameters, the blood levels of endothelin (ET) and nitric oxide (NO) were determined before and after treatment. RESULTS: After treatment of ZYTM, the hemorrheologic and hemodynamic parameters were all significantly improved (P < 0.01 or P < 0.05), the therapeutic effect of ZYTM was better than that of Naoluotong (P < 0.05), compared with the control group after treatment, the level of ET in the treated group were lower (P < 0.01), and level of NO were higher (P < 0.01). CONCLUSION:ZYTM has good effect in treating senile cerebral infarction.