Literature DB >> 15810455

[Protection of puerarin on the cerebral injury in the rats with acute local ischemia].

Hong-Ping Pan1, Jia-Zhen Yang, Xiang-Lan Mo, Lu-Li Li, Zhen-Lu Huang, Jing Ye, Jin Huang.   

Abstract

OBJECTIVE: To study the protection of puerarin on the cerebral injury in the rats with acute local ischemia.
METHOD: Rat was evaluated model of acute local cerebral ischemia was made by ligating middle cerebral artery. The cerebral damage toxylin and eosin((HE). RESULT: The number of died neurons were significantly less in puerarin-treated rats than in the rats with cerebral ischemia (P < 0. 05). Similarly, the cerebral edema were significantly attenuated in the puerarin-treated rats as compared with cerebrally ischemic rats.
CONCLUSION: Puerarin can prevent the neuron from damage induced by acute cerebral ischemia.

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Year:  2005        PMID: 15810455

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  3 in total

1.  Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by inhibiting the inflammatory response.

Authors:  Feng Zhou; Liang Wang; Panpan Liu; Weiwei Hu; Xiangdong Zhu; Hong Shen; Yuanyuan Yao
Journal:  Neural Regen Res       Date:  2014-12-01       Impact factor: 5.135

2.  Comparative pharmacokinetics of five saponins after intravenous administration of TSFS injection and TSFS injection plus TFFG in rats under different physiological states.

Authors:  Xiao-Ming Liu; Xing Zhao; En-Ze Gao; Yun-Li Zhao; Zheng Liu; Zhi-Guo Yu
Journal:  J Pharm Anal       Date:  2013-03-27

3.  Puerarin attenuates ovalbumin-induced lung inflammation and hemostatic unbalance in rat asthma model.

Authors:  Feng Dong; Chengbin Wang; Jinyan Duan; Weiyi Zhang; Daijun Xiang; Mianyang Li
Journal:  Evid Based Complement Alternat Med       Date:  2014-01-02       Impact factor: 2.629

  3 in total

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