| Literature DB >> 1581018 |
G T Van Kempen1, P C Molenaar.
Abstract
Clinical evidence suggests that endocrinal factors are involved in fluctuations of the symptoms of women with myasthenia gravis. We studied the effect of estradiol and progesterone in an animal model for myasthenia gravis in rats. Although it was found that the mass of muscles was dependent on sex, and in female rats affected by estradiol, the number of acetylcholine receptors in these muscles was independent of sex and hormone administration. Sex hormones failed to influence the severity of muscle weakness in myasthenic rats.Entities:
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Year: 1992 PMID： 1581018 DOI： 10.1007/bf01245365
Source DB: PubMed Journal: J Neural Transm Gen Sect