Literature DB >> 15809853

[Incidence of transmission of pathogens in intensive care units. Results of the SIR 3 study].

S Bärwolff1, H Grundmann, F Schwab, A Tami, M Behnke, C Geffers, E Halle, U Göbel, R Schiller, D Jonas, I Klare, K Weist, W Witte, E Dinger, K Beilecke, H Rüden, P Gastmeier.   

Abstract

The objective of this study was to determine the incidence of episodes of transmission of nosocomial pathogens and of those pathogens leading to nosocomial infections. Over a period of 18 months all patients from 5 intensive care units (ICUs) who stayed for more than 2 days were included in this study. Surveillance of nosocomial infections was carried out and all isolates of 10 of the most frequent pathogens in ICUs (indicator pathogens) were collected and typed. A total of 28,498 patient days and 431 nosocomial infections were observed (incidence density 15.1 per 1,000 patient days), among them 278 caused by 1 of the selected indicator pathogens. A total of 141 episodes of transmissions were identified, corresponding to an incidence of episodes of transmission of 5.0 per 1,000 patient days and 41 nosocomial infections were transmission-associated, corresponding to 14.5% of all nosocomial infections. The data of this study demonstrate that even in ICUs with average nosocomial infection rates, some nosocomial infections could be avoided.

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Year:  2005        PMID: 15809853     DOI: 10.1007/s00101-005-0848-8

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  18 in total

1.  Detection of cross-transmission of multiresistant Gram-negative bacilli and Staphylococcus aureus in adult intensive care units by routine typing of clinical isolates.

Authors:  Hajo Grundmann; Axel Hahn; Boris Ehrenstein; Klaus Geiger; Hansjörg Just; Franz D. Daschner
Journal:  Clin Microbiol Infect       Date:  1999-07       Impact factor: 8.067

2.  National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2003, issued August 2003.

Authors: 
Journal:  Am J Infect Control       Date:  2003-12       Impact factor: 2.918

3.  [Surveillance of nosocomial infections in intensive care units. Current data and interpretations].

Authors:  Petra Gastmeier; Christine Geffers; Dorit Sohr; Frank Schwab; Michael Behnke; Henning Rüden
Journal:  Wien Klin Wochenschr       Date:  2003-02-28       Impact factor: 1.704

4.  Characteristics of polyclonal endemicity of Pseudomonas aeruginosa colonization in intensive care units. Implications for infection control.

Authors:  M J Bonten; D C Bergmans; H Speijer; E E Stobberingh
Journal:  Am J Respir Crit Care Med       Date:  1999-10       Impact factor: 21.405

5.  How many nosocomial infections are associated with cross-transmission? A prospective cohort study in a surgical intensive care unit.

Authors:  Klaus Weist; Kathrin Pollege; Ines Schulz; Henning Rüden; Petra Gastmeier
Journal:  Infect Control Hosp Epidemiol       Date:  2002-03       Impact factor: 3.254

6.  CDC definitions for nosocomial infections, 1988.

Authors:  J S Garner; W R Jarvis; T G Emori; T C Horan; J M Hughes
Journal:  Am J Infect Control       Date:  1988-06       Impact factor: 2.918

7.  How many infections are caused by patient-to-patient transmission in intensive care units?

Authors:  Hajo Grundmann; Sina Bärwolff; Adriana Tami; Michael Behnke; Frank Schwab; Christine Geffers; Elke Halle; Ulf B Göbel; Reinhold Schiller; Daniel Jonas; Ingo Klare; Klaus Weist; Wolfgang Witte; Kathrin Beck-Beilecke; Martin Schumacher; Henning Rüden; Petra Gastmeier
Journal:  Crit Care Med       Date:  2005-05       Impact factor: 7.598

8.  Multicenter study using standardized protocols and reagents for evaluation of reproducibility of PCR-based fingerprinting of Acinetobacter spp.

Authors:  H J Grundmann; K J Towner; L Dijkshoorn; P Gerner-Smidt; M Maher; H Seifert; M Vaneechoutte
Journal:  J Clin Microbiol       Date:  1997-12       Impact factor: 5.948

9.  Comparison of PCR-based methods for typing Escherichia coli.

Authors:  D Jonas; B Spitzmüller; K Weist; H Rüden; F D Daschner
Journal:  Clin Microbiol Infect       Date:  2003-08       Impact factor: 8.067

10.  The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee.

Authors:  J L Vincent; D J Bihari; P M Suter; H A Bruining; J White; M H Nicolas-Chanoin; M Wolff; R C Spencer; M Hemmer
Journal:  JAMA       Date:  1995 Aug 23-30       Impact factor: 56.272

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  2 in total

1.  [Infection-inflammation-sepsis: state of the art and future perspectives. Tübingen Intensive Symposium, 08.10.2005].

Authors:  F Schröder; W A Krueger
Journal:  Anaesthesist       Date:  2006-07       Impact factor: 1.041

2.  Cross-transmission rates of enterococcal isolates among newborns in a neonatal intensive care unit.

Authors:  Henning Böhme; Chitra Königsmark; Ingo Klare; Melanie Zischka; Guido Werner
Journal:  Pediatr Rep       Date:  2012-03-26
  2 in total

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