Literature DB >> 15808914

The effects of neurotensin on selected parameters of lipid metabolism in rats.

J Piatek1, H Witmanowski, J Paluszak, H Krauss, J Krawczyk.   

Abstract

15 nM/kg b.m. of neurotensin (NT) caused a significant inhibition of LMA within 30 min of administration and this effect persisted up for to the 240 th minute of the experiment. A 15 nM/kgb.m. dose also caused a reduction in SLA which persisted up to the 120 th minute. Sixty minutes after an intraperitoneal administration of NT a decrease in the cholesterol and NEFA levels and an increase in the TG and glycerol levels were observed. These effects were inhibited by the NTR2-blocker (levocabastine) and were not subject to change after an in vivo application of SR 48692.

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Year:  2005        PMID: 15808914     DOI: 10.1016/j.peptides.2004.12.005

Source DB:  PubMed          Journal:  Peptides        ISSN: 0196-9781            Impact factor:   3.750


  2 in total

1.  High pro-neurotensin levels in individuals with type 1 diabetes associate with the development of cardiovascular risk factors at follow-up.

Authors:  Flavia Agata Cimini; Ilaria Barchetta; Laura Bertoccini; Valentina Ceccarelli; Marco Giorgio Baroni; Olle Melander; Maria Gisella Cavallo
Journal:  Acta Diabetol       Date:  2021-08-29       Impact factor: 4.280

2.  Neurotensin Is a Lipid-Induced Gastrointestinal Peptide Associated with Visceral Adipose Tissue Inflammation in Obesity.

Authors:  Ilaria Barchetta; Flavia Agata Cimini; Danila Capoccia; Laura Bertoccini; Valentina Ceccarelli; Caterina Chiappetta; Frida Leonetti; Claudio Di Cristofano; Gianfranco Silecchia; Marju Orho-Melander; Olle Melander; Maria Gisella Cavallo
Journal:  Nutrients       Date:  2018-04-23       Impact factor: 5.717

  2 in total

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