OBJECTIVE: To determine the frequency of G6PD deficiency in young healthy adult males of some ethnic groups in Pakistan. DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Study performed in Combined Military Hospital, Attock in collaboration with Armed Forces Institute of Pathology, Rawalpindi from October 2003 to January 2004. PATIENTS AND METHODS: Asymptomatic and healthy adult males were included in the study. A brief clinical record including age, ethnic group, place of residence, and history of past illnesses including fever, episodes of recurrent jaundice were recorded. Met-hemoglobin reduction test for G6PD screening was performed. Hemoglobin, red cell indices and total leukocyte count of G6PD deficient cases were measured on Sysmex KX 32 hematology analyzer. RESULTS: Three thousand adult males with age between 17 years to 23 years were screened. G6PD deficiency was detected in 1.8%. Deficiency state was 1.07% in Kashmiris, 1.47% in Punjabis, 2.77% in Sindhis, and 3.17% in Pathans. Past history of recurrent jaundice was present in 5.7%. Mild anemia was present in 3.8%. CONCLUSION: Frequency of G6PD deficiency was 1.8% in young healthy adults with insignificant difference among various ethnic groups except in Pathans.
OBJECTIVE: To determine the frequency of G6PD deficiency in young healthy adult males of some ethnic groups in Pakistan. DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Study performed in Combined Military Hospital, Attock in collaboration with Armed Forces Institute of Pathology, Rawalpindi from October 2003 to January 2004. PATIENTS AND METHODS: Asymptomatic and healthy adult males were included in the study. A brief clinical record including age, ethnic group, place of residence, and history of past illnesses including fever, episodes of recurrent jaundice were recorded. Met-hemoglobin reduction test for G6PD screening was performed. Hemoglobin, red cell indices and total leukocyte count of G6PD deficient cases were measured on Sysmex KX 32 hematology analyzer. RESULTS: Three thousand adult males with age between 17 years to 23 years were screened. G6PD deficiency was detected in 1.8%. Deficiency state was 1.07% in Kashmiris, 1.47% in Punjabis, 2.77% in Sindhis, and 3.17% in Pathans. Past history of recurrent jaundice was present in 5.7%. Mild anemia was present in 3.8%. CONCLUSION: Frequency of G6PD deficiency was 1.8% in young healthy adults with insignificant difference among various ethnic groups except in Pathans.
Authors: Toby Leslie; Ismail Mayan; Nasir Mohammed; Panna Erasmus; Jan Kolaczinski; Christopher J M Whitty; Mark Rowland Journal: PLoS One Date: 2008-08-06 Impact factor: 3.240
Authors: Bushra Moiz; Haroon Muhammad Arshad; Ahmed Raheem; Hasan Hayat; Najia Karim Ghanchi; M Asim Beg Journal: Malar J Date: 2017-10-24 Impact factor: 2.979