Literature DB >> 15807662

Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology.

M F Ross1, G F Kelso, F H Blaikie, A M James, H M Cochemé, A Filipovska, T Da Ros, T R Hurd, R A J Smith, M P Murphy.   

Abstract

Lipophilic phosphonium cations were first used to investigate mitochondrial biology by Vladimir Skulachev and colleagues in the late 1960s. Since then, these molecules have become important tools for exploring mitochondrial bioenergetics and free radical biology. Here we review why these molecules are useful in mitochondrial research and outline some of the ways in which they are now being utilized.

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Year:  2005        PMID: 15807662     DOI: 10.1007/s10541-005-0104-5

Source DB:  PubMed          Journal:  Biochemistry (Mosc)        ISSN: 0006-2979            Impact factor:   2.487


  113 in total

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