OBJECTIVE: To elucidate the effects of exopolysaccharide from Tolypocladium sinense on murine immunocytes in vitro. METHODS: Extracted exopolysccharide (EPS) from cultured Tolypocladium sinense. The effects of EPS on mouse immune parameters were detected in vitro using cell culture techniques. RESULTS: The results indicated that EPS might significantly not only promote mouse macrophage neutral red uptake ability and cytotoxicity (P < 0.05), but also stimulate their thymus lymphocytes proliferation (P < 0.05). CONCLUSION: EPS may elevate murine cellular immunity to a certain.
OBJECTIVE: To elucidate the effects of exopolysaccharide from Tolypocladium sinense on murine immunocytes in vitro. METHODS: Extracted exopolysccharide (EPS) from cultured Tolypocladium sinense. The effects of EPS on mouse immune parameters were detected in vitro using cell culture techniques. RESULTS: The results indicated that EPS might significantly not only promote mouse macrophage neutral red uptake ability and cytotoxicity (P < 0.05), but also stimulate their thymus lymphocytes proliferation (P < 0.05). CONCLUSION:EPS may elevate murine cellular immunity to a certain.