| Literature DB >> 15802835 |
Viqar Uddin Ahmad1, Afsar Khan, Umar Farooq, Farzana Kousar, Saleha Suleman Khan, Sarfraz Ahmad Nawaz, Muhammad Athar Abbasi, Muhammad Iqbal Choudhary.
Abstract
Three new tricyclic cis-clerodane type diterpenoids trivially named as limbatolide A (1), limbatolide B (2) and limbatolide C (3) have been isolated from the roots of Otostegia limbata along with two known compounds; oleanic acid and beta-sitosterol. The structure elucidation of the new compounds was based primarily on two-dimensional (2D) NMR techniques. Compounds 1-3 displayed inhibitory potential in a concentration-dependent manner against acetylcholinesterase (AChE; EC 3.1.1.7) and butyrylcholinesterase (BChE; EC 3.1.1.8) enzymes, respectively.Entities:
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Year: 2005 PMID： 15802835 DOI： 10.1248/cpb.53.378
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645