Literature DB >> 15801603

Diclofenac poisoning is widespread in declining vulture populations across the Indian subcontinent.

Susanne Shultz1, Hem Sagar Baral, Sheonaidh Charman, Andrew A Cunningham, Devojit Das, G R Ghalsasi, Mallikarjun S Goudar, Rhys E Green, Ainsley Jones, Prashant Nighot, Deborah J Pain, Vibhu Prakash.   

Abstract

Recent declines in the populations of three species of vultures in the Indian subcontinent are among the most rapid ever recorded in any bird species. Evidence from a previous study of one of these species, Gyps bengalensis, in the Punjab province of Pakistan, strongly implicates mortality caused by ingestion of residues of the veterinary non-steroidal anti-inflammatory drug diclofenac as the major cause of the decline. We show that a high proportion of Gyps bengalensis and G. indicus found dead or dying in a much larger area of India and Nepal also have residues of diclofenac and visceral gout, a post-mortem finding that is strongly associated with diclofenac contamination in both species. Hence, veterinary use of diclofenac is likely to have been the major cause of the rapid vulture population declines across the subcontinent.

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Year:  2004        PMID: 15801603      PMCID: PMC1810094          DOI: 10.1098/rsbl.2004.0223

Source DB:  PubMed          Journal:  Proc Biol Sci        ISSN: 0962-8452            Impact factor:   5.349


  1 in total

1.  Diclofenac residues as the cause of vulture population decline in Pakistan.

Authors:  J Lindsay Oaks; Martin Gilbert; Munir Z Virani; Richard T Watson; Carol U Meteyer; Bruce A Rideout; H L Shivaprasad; Shakeel Ahmed; Muhammad Jamshed Iqbal Chaudhry; Muhammad Arshad; Shahid Mahmood; Ahmad Ali; Aleem Ahmed Khan
Journal:  Nature       Date:  2004-01-28       Impact factor: 49.962

  1 in total
  29 in total

1.  NSAIDs and scavenging birds: potential impacts beyond Asia's critically endangered vultures.

Authors:  Richard Cuthbert; Jemima Parry-Jones; Rhys E Green; Deborah J Pain
Journal:  Biol Lett       Date:  2007-02-22       Impact factor: 3.703

2.  Direct evidence of poison-driven widespread population decline in a wild vertebrate.

Authors:  Patricia Mateo-Tomás; Pedro P Olea; Eva Mínguez; Rafael Mateo; Javier Viñuela
Journal:  Proc Natl Acad Sci U S A       Date:  2020-06-29       Impact factor: 11.205

3.  Avian scavengers and the threat from veterinary pharmaceuticals.

Authors:  Richard J Cuthbert; Mark A Taggart; Vibhu Prakash; Soumya S Chakraborty; Parag Deori; Toby Galligan; Mandar Kulkarni; Sachin Ranade; Mohini Saini; Anil Kumar Sharma; Rohan Shringarpure; Rhys E Green
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2014-11-19       Impact factor: 6.237

4.  Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts.

Authors:  Rajeshwary Ghosh; Sumanta K Goswami; Luis Felipe B B Feitoza; Bruce Hammock; Aldrin V Gomes
Journal:  Int J Cardiol       Date:  2016-08-13       Impact factor: 4.164

Review 5.  Comparative metabolism as a key driver of wildlife species sensitivity to human and veterinary pharmaceuticals.

Authors:  Thomas H Hutchinson; Judith C Madden; Vinny Naidoo; Colin H Walker
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2014-11-19       Impact factor: 6.237

6.  Toxicity of diclofenac to Gyps vultures.

Authors:  Gerry E Swan; Richard Cuthbert; Miguel Quevedo; Rhys E Green; Deborah J Pain; Paul Bartels; Andrew A Cunningham; Neil Duncan; Andrew A Meharg; J Lindsay Oaks; Jemima Parry-Jones; Susanne Shultz; Mark A Taggart; Gerhard Verdoorn; Kerri Wolter
Journal:  Biol Lett       Date:  2006-06-22       Impact factor: 3.703

7.  Exposure of Threatened Accipitridae to Mycobacterium bovis Calls for Active Surveillance.

Authors:  Mónica V Cunha; Beatriz Azorín; Rocío G Peñuela; Teresa Albuquerque; Ana Botelho
Journal:  Ecohealth       Date:  2017-03-03       Impact factor: 3.184

Review 8.  Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go.

Authors:  Andrew K Hotchkiss; Cynthia V Rider; Chad R Blystone; Vickie S Wilson; Phillip C Hartig; Gerald T Ankley; Paul M Foster; Clark L Gray; L Earl Gray
Journal:  Toxicol Sci       Date:  2008-02-16       Impact factor: 4.849

9.  Diclofenac-induced biochemical and histopathological changes in white leghorn birds (Gallus domesticus).

Authors:  Teenu Jain; K M Koley; V P Vadlamudi; R C Ghosh; S Roy; Sandhya Tiwari; Upasana Sahu
Journal:  Indian J Pharmacol       Date:  2009-10       Impact factor: 1.200

10.  Vulture mortality resulting from illegal poisoning in the southern Balkan Peninsula.

Authors:  Dimitar Parvanov; Emilian Stoynov; Nadya Vangelova; Hristo Peshev; Atanas Grozdanov; Ventseslav Delov; Yavor Iliev
Journal:  Environ Sci Pollut Res Int       Date:  2017-11-03       Impact factor: 4.223

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