| Literature DB >> 15801034 |
Adam Mor1, Clifton O Bingham, Clifton Bingham, Laura Barisoni, Eileen Lydon, H Michael Belmont.
Abstract
Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine. Agents that neutralize TNF-alpha are effective in the treatment of disorders such as rheumatoid arthritis, juvenile rheumatoid arthritis (JRA), spondyloarthropathies, and inflammatory bowel disease. TNF-alpha antagonist therapy has been associated with the development of antinuclear antibodies (ANA) and double-stranded DNA (dsDNA) antibodies, as well as the infrequent development of systemic lupus erythematosus (SLE)-like disease. We describe the first case of biopsy-confirmed proliferative lupus nephritis and leukocytoclastic vasculitis in a patient treated with etanercept for JRA.Entities:
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Year: 2005 PMID: 15801034
Source DB: PubMed Journal: J Rheumatol ISSN: 0315-162X Impact factor: 4.666