Literature DB >> 15800133

Mind, brain, and personality disorders.

Glen O Gabbard1.   

Abstract

OBJECTIVE: The use of the terms "mind" and "brain" in psychiatry is often associated with a set of polarities. Concepts such as environment, psychosocial, and psychotherapy are linked with "mind," while genes, biology, and medication are often associated with "brain." The author examines these dichotomies as they apply to personality disorders.
METHOD: Research on antisocial and borderline personality disorders that is relevant to these dichotomies is evaluated. The implications of the findings for the understanding of pathogenesis and treatment are reconsidered.
RESULTS: In the clinical setting, it is problematic to lump together terms such as "genes," "brain," and "biological" as though they are separate and distinct from terms such as "environment," "mind," and "psychosocial." These dichotomies are problematic, because genes and environment are inextricably intertwined in the pathogenesis of personality disorders, psychosocial experiences may result in permanent changes in the brain, and psychotherapy may have its effect by altering brain structure and function. The "theory of mind" is a useful construct for bridging "mind" and "brain" in the treatment of personality disorders.
CONCLUSIONS: Severe personality disorders are best understood and treated without "either-or" dichotomies of brain and mind. Each domain has a different language, however, and the language of the mind is necessary to help the patient develop a theory of mind.

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Year:  2005        PMID: 15800133     DOI: 10.1176/appi.ajp.162.4.648

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  8 in total

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2.  The characterization of beliefs in obsessive-compulsive disorder.

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3.  Relationships of Homophobic Bullying Victimization during Childhood with Borderline Personality Disorder Symptoms in Early Adulthood among Gay and Bisexual Men: Mediating Effect of Depressive Symptoms and Moderating Effect of Family Support.

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Journal:  Int J Environ Res Public Health       Date:  2022-04-14       Impact factor: 4.614

Review 4.  Neuroimaging and genetics of borderline personality disorder: a review.

Authors:  Eric Lis; Brian Greenfield; Melissa Henry; Jean Marc Guilé; Geoffrey Dougherty
Journal:  J Psychiatry Neurosci       Date:  2007-05       Impact factor: 6.186

5.  Mirror neuron system.

Authors:  V Rajmohan; E Mohandas
Journal:  Indian J Psychiatry       Date:  2007-01       Impact factor: 1.759

Review 6.  Treatment consideration and manifest complexity in comorbid neuropsychiatric disorders.

Authors:  Tomas Palomo; Richard M Kostrzewa; Richard J Beninger; Trevor Archer
Journal:  Neurotox Res       Date:  2007-07       Impact factor: 3.911

7.  Neurobiology of spirituality.

Authors:  E Mohandas
Journal:  Mens Sana Monogr       Date:  2008-01

8.  The presence of both serotonin 1A receptor (HTR1A) and dopamine transporter (DAT1) gene variants increase the risk of borderline personality disorder.

Authors:  Peter R Joyce; John Stephenson; Martin Kennedy; Roger T Mulder; Patrick C McHugh
Journal:  Front Genet       Date:  2014-01-07       Impact factor: 4.599

  8 in total

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