| Literature DB >> 15799874 |
Corinne Planchamp1, Gerd J Beyer, Daniel O Slosman, François Terrier, Catherine M Pastor.
Abstract
The aim was to study the influence of temperature on the transport of the hepatobiliary contrast agent Gadobenate dimeglumine (Gd-BOPTA). Rat livers were isolated and perfused with Gd-BOPTA at 12, 25, 30, 36 and 38 degrees C. After the perfusion period, biopsies were collected and the MR signal intensity was measured. Uptake and biliary excretion were quantified with radiolabeled Gd-BOPTA. MR signal intensity decreased with temperature of perfusion. This phenomenon was appropriately quantified with 153Gd and 153Sm labeling, in contrast to 67Ga.Entities:
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Year: 2005 PMID： 15799874 DOI： 10.1016/j.apradiso.2004.11.002
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513