| Literature DB >> 1579807 |
R M Sudderick1, V J Lund, J P Thomson, A McCombe, I S Mackay.
Abstract
Nineteen patients presenting for sinus surgery were studied to evaluate the percentage penetration from serum to paranasal sinus tissue of a single orally administered dose of cefuroxime axetil. The methods and results are presented. Cefuroxime penetrates well into human sinus mucosa following oral administration and the concentrations obtained exceed minimum inhibitory concentrations of cefuroxime for the most common pathogens in sinusitis.Entities:
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Year: 1992 PMID： 1579807
Source DB: PubMed Journal: Rhinology ISSN： 0300-0729 Impact factor: 3.681