| Literature DB >> 15797836 |
Vanessa Zuzarte-Luis1, Juan M Hurle.
Abstract
The developing limb bud provides one of the best examples in which programmed cell death exerts major morphogenetic functions. In this work, we revise the distribution and the developmental significance of cell death in the embryonic vertebrate limb and its control by the BMP signalling pathway. In addition, paying special attention to the interdigital apoptotic zones, we review current data concerning the intracellular death machinery implicated in mesodermal limb apoptosis.Entities:
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Year: 2005 PMID: 15797836 DOI: 10.1016/j.semcdb.2004.12.004
Source DB: PubMed Journal: Semin Cell Dev Biol ISSN: 1084-9521 Impact factor: 7.727