Literature DB >> 15797836

Programmed cell death in the embryonic vertebrate limb.

Vanessa Zuzarte-Luis1, Juan M Hurle.   

Abstract

The developing limb bud provides one of the best examples in which programmed cell death exerts major morphogenetic functions. In this work, we revise the distribution and the developmental significance of cell death in the embryonic vertebrate limb and its control by the BMP signalling pathway. In addition, paying special attention to the interdigital apoptotic zones, we review current data concerning the intracellular death machinery implicated in mesodermal limb apoptosis.

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Year:  2005        PMID: 15797836     DOI: 10.1016/j.semcdb.2004.12.004

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN: 1084-9521            Impact factor:   7.727


  30 in total

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Review 8.  Genetic control of programmed cell death during animal development.

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