| Literature DB >> 15797506 |
Takashi Kobayashi1, Akihiko Yoshimura.
Abstract
It has recently been shown that small interfering RNA (siRNA)-mediated inhibition of suppressors of cytokine signalling 1 (SOCS1) function enhances the immunostimulatory capacity of dendritic cells (DCs), which leads to more effective cancer vaccination. This recent study demonstrates the importance of negative regulation of DC maturation and functions for DC-based immunotherapy.Entities:
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Year: 2005 PMID： 15797506 DOI： 10.1016/j.it.2005.02.004
Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687