Literature DB >> 15797209

Scratch n' screen for inhibitors of cell migration.

Jon Soderholm1, Rebecca Heald.   

Abstract

Yarrow et al. have identified a small molecule inhibitor of cell migration, 3-(4-pyridyl)indole ("Rockout"), that targets Rho-kinase via a novel screening method using a scratch wound healing assay adapted to a high-throughput format and automated microscopy.

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Year:  2005        PMID： 15797209     DOI： 10.1016/j.chembiol.2005.03.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  9 in total

1.  A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model.

Authors:  Luciana B Lopes; Colleen M Brophy; Charles R Flynn; Zhengping Yi; Benjamin P Bowen; Christopher Smoke; Brandon Seal; Alyssa Panitch; Padmini Komalavilas
Journal:  J Vasc Surg       Date:  2010-09-22       Impact factor: 4.268

2.  The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells.

Authors:  Hermann Kalwa; Thomas Michel
Journal:  J Biol Chem       Date:  2010-11-20       Impact factor: 5.157

Review 3.  Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways.

Authors:  Christopher M Evans; Tasha E Fingerlin; Marvin I Schwarz; David Lynch; Jonathan Kurche; Laura Warg; Ivana V Yang; David A Schwartz
Journal:  Physiol Rev       Date:  2016-10       Impact factor: 37.312

4.  Mechanisms of microvascular wound repair I. Role of mitosis, oxygen tension, and I-kappa B.

Authors:  Vaishali Chaudhuri; Brian R Potts; Marvin A Karasek
Journal:  In Vitro Cell Dev Biol Anim       Date:  2006 Nov-Dec       Impact factor: 2.416

5.  Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes.

Authors:  Jeremy P Goering; Dona Greta Isai; Andras Czirok; Irfan Saadi
Journal:  J Vis Exp       Date:  2021-02-13       Impact factor: 1.355

6.  Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro.

Authors:  Jakob Karén; Alejandro Rodriguez; Tomas Friman; Lennart Dencker; Christian Sundberg; Birger Scholz
Journal:  PLoS One       Date:  2011-09-22       Impact factor: 3.240

7.  Wound healing revised: a novel reepithelialization mechanism revealed by in vitro and in silico models.

Authors:  Kai Safferling; Thomas Sütterlin; Kathi Westphal; Claudia Ernst; Kai Breuhahn; Merlin James; Dirk Jäger; Niels Halama; Niels Grabe
Journal:  J Cell Biol       Date:  2013-11-25       Impact factor: 10.539

8.  Surface acoustic waves enhance neutrophil killing of bacteria.

Authors:  John D Loike; Anna Plitt; Komal Kothari; Jona Zumeris; Sadna Budhu; Kaitlyn Kavalus; Yonatan Ray; Harold Jacob
Journal:  PLoS One       Date:  2013-08-06       Impact factor: 3.240

9.  A high-throughput three-dimensional cell migration assay for toxicity screening with mobile device-based macroscopic image analysis.

Authors:  David M Timm; Jianbo Chen; David Sing; Jacob A Gage; William L Haisler; Shane K Neeley; Robert M Raphael; Mehdi Dehghani; Kevin P Rosenblatt; T C Killian; Hubert Tseng; Glauco R Souza
Journal:  Sci Rep       Date:  2013-10-21       Impact factor: 4.379
  9 in total

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