Literature DB >> 15797012

Synaptogenesis: a balancing act between excitation and inhibition.

Hollis Cline1.   

Abstract

Recent studies have implicated a number of membrane-associated proteins, including the signaling pair neuroligin and beta-neurexin, in synapse formation, suggesting that they govern the ratio of inhibitory and excitatory synapses on CNS neurons. These findings, together with data indicating that the genes encoding neuroligin and PSD95 are altered in autism patients, suggest that a molecular understanding of complex neurological diseases is within reach.

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Year:  2005        PMID: 15797012     DOI: 10.1016/j.cub.2005.03.010

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  54 in total

1.  Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.

Authors:  Philippe Leone; Davide Comoletti; Géraldine Ferracci; Sandrine Conrod; Simon U Garcia; Palmer Taylor; Yves Bourne; Pascale Marchot
Journal:  EMBO J       Date:  2010-06-11       Impact factor: 11.598

Review 2.  CNS immune privilege: hiding in plain sight.

Authors:  Monica J Carson; Jonathan M Doose; Benoit Melchior; Christoph D Schmid; Corinne C Ploix
Journal:  Immunol Rev       Date:  2006-10       Impact factor: 12.988

3.  Crystal structure of the second LNS/LG domain from neurexin 1alpha: Ca2+ binding and the effects of alternative splicing.

Authors:  Lauren R Sheckler; Lisa Henry; Shuzo Sugita; Thomas C Südhof; Gabby Rudenko
Journal:  J Biol Chem       Date:  2006-06-13       Impact factor: 5.157

Review 4.  MAGUKs, synaptic development, and synaptic plasticity.

Authors:  Chan-Ying Zheng; Gail K Seabold; Martin Horak; Ronald S Petralia
Journal:  Neuroscientist       Date:  2011-04-15       Impact factor: 7.519

5.  Wiring optimization can relate neuronal structure and function.

Authors:  Beth L Chen; David H Hall; Dmitri B Chklovskii
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-14       Impact factor: 11.205

6.  Regulation of neurexin 1beta tertiary structure and ligand binding through alternative splicing.

Authors:  Kaiser C Shen; Dorota A Kuczynska; Irene J Wu; Beverly H Murray; Lauren R Sheckler; Gabby Rudenko
Journal:  Structure       Date:  2008-03       Impact factor: 5.006

7.  GAD65 Promoter Polymorphism rs2236418 Modulates Harm Avoidance in Women via Inhibition/Excitation Balance in the Rostral ACC.

Authors:  Lejla Colic; Meng Li; Liliana Ramona Demenescu; Shija Li; Iris Müller; Anni Richter; Gusalija Behnisch; Constanze I Seidenbecher; Oliver Speck; Björn H Schott; Oliver Stork; Martin Walter
Journal:  J Neurosci       Date:  2018-05-03       Impact factor: 6.167

8.  An adaptive role for BDNF Val66Met polymorphism in motor recovery in chronic stroke.

Authors:  Luye Qin; Deqiang Jing; Sarah Parauda; Jason Carmel; Rajiv R Ratan; Francis S Lee; Sunghee Cho
Journal:  J Neurosci       Date:  2014-02-12       Impact factor: 6.167

9.  Developmental changes in plasticity, synaptic, glia and connectivity protein levels in rat dorsal hippocampus.

Authors:  Alessio Travaglia; Reto Bisaz; Emmanuel Cruz; Cristina M Alberini
Journal:  Neurobiol Learn Mem       Date:  2016-08-12       Impact factor: 2.877

10.  Activity-dependent regulation of inhibitory synapse development by Npas4.

Authors:  Yingxi Lin; Brenda L Bloodgood; Jessica L Hauser; Ariya D Lapan; Alex C Koon; Tae-Kyung Kim; Linda S Hu; Athar N Malik; Michael E Greenberg
Journal:  Nature       Date:  2008-09-24       Impact factor: 49.962

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