| Literature DB >> 15797012 |
Abstract
Recent studies have implicated a number of membrane-associated proteins, including the signaling pair neuroligin and beta-neurexin, in synapse formation, suggesting that they govern the ratio of inhibitory and excitatory synapses on CNS neurons. These findings, together with data indicating that the genes encoding neuroligin and PSD95 are altered in autism patients, suggest that a molecular understanding of complex neurological diseases is within reach.Entities:
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Year: 2005 PMID: 15797012 DOI: 10.1016/j.cub.2005.03.010
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834