Literature DB >> 15796840

[Long-term result of repair of deeply burned hands with large sheet of split-thickness autoskin grafting with the preservation of denatured dermis].

Xing-Hua Yang1, Xiao-Yuan Huang, Shao-Rong Lei, Pi-Hong Zhang, Ming-Hua Zhang, Mu-Zhang Xiao, Ji-Zhang Zeng, Jian-Hong Long.   

Abstract

OBJECTIVE: To evaluate the long-term results of repair of burn hands with large sheet of split-thickness autoskin grafting with the preservation of denatured dermis.
METHODS: One hundred and fifty-two hands in 86 burn patients with deep partial thickness and full thickness burn were enrolled in the study. The burned hands were treated by tangential excision and grafted with large sheet of split-thickness autoskin with the preservation of denatured dermis. The patients were followed-up from 3 months to 3 years. The skin color, elasticity, degree of contracture and the functional grading of the operated hands were observed.
RESULTS: Good function was found in one hundred and forty-one out of the 152 burn hands (92.8%). For the rest 11 hands, pigmentation was found in 4, poor appearance in 4, and 3 hands with both poor appearance and function.
CONCLUSION: Large sheet of split-thickness autoskin grafting with the preservation of denatured dermis could be an optimal choice for the management of hands with deep partial thickness burn, and it could restore the appearance and function of the hands satisfactorily.

Entities:  

Mesh:

Year:  2005        PMID: 15796840

Source DB:  PubMed          Journal:  Zhonghua Shao Shang Za Zhi        ISSN: 1009-2587


  6 in total

1.  Let-7c miRNA Inhibits the Proliferation and Migration of Heat-Denatured Dermal Fibroblasts Through Down-Regulating HSP70.

Authors:  Tao Jiang; Xingang Wang; Weiwei Wu; Fan Zhang; Shifeng Wu
Journal:  Mol Cells       Date:  2016-02-29       Impact factor: 5.034

2.  miR-100 Inhibits the Growth and Migration of Burn-Denatured Fibroblasts.

Authors:  Jianghui Ying; Yunfeng Liu; Ruijin Yang; Yong Zhang; Jianjun Xu
Journal:  Med Sci Monit       Date:  2016-03-01

3.  MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts.

Authors:  Chun Zhang; Jinhua Dai; Youfen Fan; Xianghui He; Renxiong Wei
Journal:  Korean J Intern Med       Date:  2018-01-05       Impact factor: 2.884

4.  MicroRNA-23b Inhibits the Proliferation and Migration of Heat-Denatured Fibroblasts by Targeting Smad3.

Authors:  Xipeng Zhang; Jie Yang; Jiming Zhao; Pihong Zhang; Xiaoyuan Huang
Journal:  PLoS One       Date:  2015-07-08       Impact factor: 3.240

5.  Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury.

Authors:  Jie Zhou; Xipeng Zhang; Pengfei Liang; Licheng Ren; Jizhang Zeng; Minghua Zhang; Pihong Zhang; Xiaoyuan Huang
Journal:  Biol Open       Date:  2016-01-21       Impact factor: 2.422

6.  Autophagy promotes angiogenesis via AMPK/Akt/mTOR signaling during the recovery of heat-denatured endothelial cells.

Authors:  Pengfei Liang; Bimei Jiang; Yuanbin Li; Zhenguo Liu; Pihong Zhang; Minghua Zhang; Xiaoyuan Huang; Xianzhong Xiao
Journal:  Cell Death Dis       Date:  2018-11-19       Impact factor: 8.469

  6 in total

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