Literature DB >> 15796282

Health and economic consequences of an outbreak of pertussis among healthcare workers in a hospital in France.

Alexandra Ward1, Jaime Caro, Laurence Bassinet, Bruno Housset, Judith A O'Brien, Nicole Guiso.   

Abstract

BACKGROUND: Bordetella pertussis is highly contagious, and because immunity wanes after vaccination, it continues to be a cause of cough among adults.
OBJECTIVE: To describe the healthcare services used and productivity losses accrued by healthcare workers (HCWs) missing work due to pertussis.
METHODS: After 3 pertussis cases were confirmed among HCWs, all hospital employees and patients with a cough were screened between November 2000 and March 2001. Each potential case underwent diagnostic tests and received antibiotics (spiramycin or azithromycin) when appropriate. Symptomatic employees were not allowed to return to work until they received an antibiotic for at least 5 days. Services used (physician visits and calls, antibiotics, diagnostic tests, hospitalization, and treatment provided to their contacts) were combined with cost estimates (in 2002 euros) for these services in France.
RESULTS: Ninety-one potential cases were identified (77 HCWs, 12 patients, and 2 family members). Of them, 89% received antibiotics and 22% had at least one contact who was also treated. Approximately half (55%) of the HCWs who were cases missed 5 days of work. Four patients were admitted to the hospital as a result of the infection. The average medical cost was 297 euros per potential case: diagnostic tests accounted for 32% and hospitalization for 31%. Total cost (medical and productivity) was 46,661 euros for 91 cases, 42% from productivity losses. An investigation to identify these potential cases also accrued additional costs.
CONCLUSION: Serious adverse health and economic consequences arose from transmission of pertussis among HCWs, their families, and patients.

Entities:  

Mesh:

Year:  2005        PMID: 15796282     DOI: 10.1086/502541

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  12 in total

Review 1.  Pertussis vaccination for health care workers.

Authors:  Thomas J Sandora; Courtney A Gidengil; Grace M Lee
Journal:  Clin Microbiol Rev       Date:  2008-07       Impact factor: 26.132

2.  Proficiency program for real-time PCR diagnosis of Bordetella pertussis infections in French hospital laboratories and at the French National Reference Center for Whooping Cough and other Bordetelloses.

Authors:  Valérie Caro; Nicole Guiso; Corinne Alberti; Sandrine Liguori; Christophe Burucoa; Gérard Couetdic; Florence Doucet-Populaire; Agnès Ferroni; Sophie Papin-Gibaud; Florence Grattard; Hélène Réglier-Poupet; Josette Raymond; Catherine Soler; Sylvie Bouchet; Sandrine Charreau; Brigitte Couzon; Isabelle Leymarie; Nicole Tavares; Mathilde Choux; Edouard Bingen; Stéphane Bonacorsi
Journal:  J Clin Microbiol       Date:  2009-08-19       Impact factor: 5.948

Review 3.  The value of childhood combination vaccines: From beliefs to evidence.

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4.  Factors affecting uptake of recommended immunizations among health care workers in South Australia.

Authors:  Jane L Tuckerman; Joanne E Collins; Helen S Marshall
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5.  Seroprevalence study of B. pertussis infection in health care workers in Catalonia, Spain.

Authors:  Luis Urbiztondo; Sonia Broner; Josep Costa; Laura Rocamora; José M Bayas; Magda Campins; Maria Esteve; Eva Borras; Angela Domínguez; The Working Group For The Study Of The Immune Status In Health Care
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6.  Presenteeism: a public health hazard.

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7.  Noninvasive ventilation for patients near the end of life: what do we know and what do we need to know?

Authors:  William J Ehlenbach; J Randall Curtis
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Review 8.  Symptomatic treatment of the cough in whooping cough.

Authors:  Kay Wang; Silvana Bettiol; Matthew J Thompson; Nia W Roberts; Rafael Perera; Carl J Heneghan; Anthony Harnden
Journal:  Cochrane Database Syst Rev       Date:  2014-09-22

9.  Modelling the return on investment of preventively vaccinating healthcare workers against pertussis.

Authors:  Luqman Tariq; Marie-Josée J Mangen; Anke Hövels; Gerard Frijstein; Hero de Boer
Journal:  BMC Infect Dis       Date:  2015-02-19       Impact factor: 3.090

10.  Is the current pertussis incidence only the results of testing? A spatial and space-time analysis of pertussis surveillance data using cluster detection methods and geographically weighted regression modelling.

Authors:  Boris Kauhl; Jeanne Heil; Christian J P A Hoebe; Jürgen Schweikart; Thomas Krafft; Nicole H T M Dukers-Muijrers
Journal:  PLoS One       Date:  2017-03-09       Impact factor: 3.240

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