BACKGROUND: It is a challenge to reliably measure the lobar volumes from magnetic resonance imaging (MRI) data. OBJECTIVE: Description of a landmark-based method for volumetric segmentation of the brain into the four cerebral lobes from MR images. METHOD: The segmentation method relies on a combination of anatomical landmarks and geometrical definitions. The first step, described previously, is a segmentation of the four lobes on the surface of the brain. The internal borders between the lobes are defined on the axial slices of the brain. The intra- and inter- rater reliability was determined from the MRI scans of a group of 10 healthy control subjects measured by 2 independent raters. RESULTS: The intra-rater relative error (and intra-class correlation coefficient) of the lobar volume measures ranged from 0.81% to 3.85% (from 0.97 to 0.99). The inter-rater relative error (and intra-class correlation coefficient) ranged from 0.55% to 3.09% (from 0.94 to 0.99). CONCLUSION: This technique has been shown to have high intra- and inter-rater reliability. The current method provides a method to obtain volumetric estimates of the 4 cerebral lobes.
BACKGROUND: It is a challenge to reliably measure the lobar volumes from magnetic resonance imaging (MRI) data. OBJECTIVE: Description of a landmark-based method for volumetric segmentation of the brain into the four cerebral lobes from MR images. METHOD: The segmentation method relies on a combination of anatomical landmarks and geometrical definitions. The first step, described previously, is a segmentation of the four lobes on the surface of the brain. The internal borders between the lobes are defined on the axial slices of the brain. The intra- and inter- rater reliability was determined from the MRI scans of a group of 10 healthy control subjects measured by 2 independent raters. RESULTS: The intra-rater relative error (and intra-class correlation coefficient) of the lobar volume measures ranged from 0.81% to 3.85% (from 0.97 to 0.99). The inter-rater relative error (and intra-class correlation coefficient) ranged from 0.55% to 3.09% (from 0.94 to 0.99). CONCLUSION: This technique has been shown to have high intra- and inter-rater reliability. The current method provides a method to obtain volumetric estimates of the 4 cerebral lobes.
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Authors: Kimberly D van der Willik; Pinar Yilmaz; Annette Compter; Michael Hauptmann; Katarzyna Jóźwiak; Rikje Ruiter; Bruno H Ch Stricker; Meike W Vernooij; M Arfan Ikram; Michiel B de Ruiter; Sanne B Schagen Journal: Neuroimage Clin Date: 2020-10-13 Impact factor: 4.881
Authors: M Arfan Ikram; Aad van der Lugt; Wiro J Niessen; Peter J Koudstaal; Gabriel P Krestin; Albert Hofman; Daniel Bos; Meike W Vernooij Journal: Eur J Epidemiol Date: 2015-12-09 Impact factor: 8.082