OBJECTIVE: This study involved the assessment of the otologic and audiologic characteristics of a group of patients with Turner syndrome. STUDY DESIGN: Prospective study consisting of a questionnaire (77 of 123 responders) and an otologic and audiologic evaluation in patients with Turner syndrome (41 participants). SETTING: Tertiary academic medical setting. PATIENTS: Children, adolescents, and adults with Turner syndrome (median age, 24 yr). INTERVENTIONS: Otomicroscopy, audiometry, immittance measurements, and diagnostic imaging. RESULTS: Otologic disease is an important characteristic in Turner syndrome. Sixty-six percent of the patients studied via the questionnaire reported a history of chronic or recurrent middle ear disease. Analysis of audiometric data in 40 patients tested reveals an equal amount of normal ears (38.8%) and pure sensorineural ears (38.8%), each constituting approximately one-third of the patient population. Pure conductive losses represent only one-fifth (21.3%) of auditory abnormality encountered. CONCLUSIONS: Careful follow-up during early childhood of children with Turner syndrome is necessary to detect middle ear disease and prevent sequelae. However, long-term periodic review is mandatory even after resolution of middle ear disease to detect sensorineural hearing loss.
OBJECTIVE: This study involved the assessment of the otologic and audiologic characteristics of a group of patients with Turner syndrome. STUDY DESIGN: Prospective study consisting of a questionnaire (77 of 123 responders) and an otologic and audiologic evaluation in patients with Turner syndrome (41 participants). SETTING: Tertiary academic medical setting. PATIENTS: Children, adolescents, and adults with Turner syndrome (median age, 24 yr). INTERVENTIONS: Otomicroscopy, audiometry, immittance measurements, and diagnostic imaging. RESULTS:Otologic disease is an important characteristic in Turner syndrome. Sixty-six percent of the patients studied via the questionnaire reported a history of chronic or recurrent middle ear disease. Analysis of audiometric data in 40 patients tested reveals an equal amount of normal ears (38.8%) and pure sensorineural ears (38.8%), each constituting approximately one-third of the patient population. Pure conductive losses represent only one-fifth (21.3%) of auditory abnormality encountered. CONCLUSIONS: Careful follow-up during early childhood of children with Turner syndrome is necessary to detect middle ear disease and prevent sequelae. However, long-term periodic review is mandatory even after resolution of middle ear disease to detect sensorineural hearing loss.
Authors: Marsha L Davenport; Jackson Roush; Chunhua Liu; Anthony J Zagar; Erica Eugster; Sharon Travers; Patricia Y Fechner; Charmian A Quigley Journal: Horm Res Paediatr Date: 2010-04-27 Impact factor: 2.852
Authors: R Bergamaschi; C Bergonzoni; L Mazzanti; E Scarano; F Mencarelli; F Messina; M Rosano; L Iughetti; A Cicognani Journal: J Endocrinol Invest Date: 2008-09 Impact factor: 4.256
Authors: Tomoko Makishima; Kelly King; Carmen C Brewer; Christopher K Zalewski; John Butman; Vladimir K Bakalov; Carolyn Bondy; Andrew J Griffith Journal: Int J Pediatr Otorhinolaryngol Date: 2009-09-03 Impact factor: 1.675