Literature DB >> 15793149

Antifungal activity of flocculosin, a novel glycolipid isolated from Pseudozyma flocculosa.

Benjamin Mimee1, Caroline Labbé, René Pelletier, Richard R Bélanger.   

Abstract

Flocculosin, a glycolipid isolated from the yeast-like fungus Pseudozyma flocculosa, was investigated for in vitro antifungal activity. The compound displayed antifungal properties against several pathogenic yeasts. Synergistic activity was observed between flocculosin and amphotericin B, and no significant cytotoxicity was demonstrated when tested against human cell lines.

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Year:  2005        PMID： 15793149      PMCID： PMC1068648          DOI： 10.1128/AAC.49.4.1597-1599.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

Review 1.  Amphotericin B nephrotoxicity.

Authors:  Gilbert Deray
Journal:  J Antimicrob Chemother       Date:  2002-02       Impact factor: 5.790

Review 2.  Antifungal agents: chemotherapeutic targets and immunologic strategies.

Authors:  N H Georgopapadakou; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

Review 3.  New antifungal agents and preparations.

Authors:  B E De Pauw
Journal:  Int J Antimicrob Agents       Date:  2000-10       Impact factor: 5.283

4.  Antifungal activity of amphotericin B cochleates against Candida albicans infection in a mouse model.

Authors:  L Zarif; J R Graybill; D Perlin; L Najvar; R Bocanegra; R J Mannino
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

5.  In vitro antifungal and fungicidal activities and erythrocyte toxicities of cyclic lipodepsinonapeptides produced by Pseudomonas syringae pv. syringae.

Authors:  K N Sorensen; K H Kim; J Y Takemoto
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

6.  Insertional mutagenesis of a fungal biocontrol agent led to discovery of a rare cellobiose lipid with antifungal activity.

Authors:  Yali Cheng; David J McNally; Caroline Labbé; Normand Voyer; François Belzile; Richard R Bélanger
Journal:  Appl Environ Microbiol       Date:  2003-05       Impact factor: 4.792

7.  New colorimetric cytotoxicity assay for anticancer-drug screening.

Authors:  P Skehan; R Storeng; D Scudiero; A Monks; J McMahon; D Vistica; J T Warren; H Bokesch; S Kenney; M R Boyd
Journal:  J Natl Cancer Inst       Date:  1990-07-04       Impact factor: 13.506

Review 8.  Antifungal drug resistance to azoles and polyenes.

Authors:  Mar Masiá Canuto; Félix Gutiérrez Rodero
Journal:  Lancet Infect Dis       Date:  2002-09       Impact factor: 25.071

Review 9.  Current and emerging azole antifungal agents.

Authors:  D J Sheehan; C A Hitchcock; C M Sibley
Journal:  Clin Microbiol Rev       Date:  1999-01       Impact factor: 26.132

Review 10.  Newer systemic antifungal agents : pharmacokinetics, safety and efficacy.

Authors:  Helen W Boucher; Andreas H Groll; Christine C Chiou; Thomas J Walsh
Journal:  Drugs       Date:  2004       Impact factor: 9.546
  10 in total
  17 in total

1.  Extracellular antifungal glycolipids of Cryptococcus humicola yeasts.

Authors:  E V Kulakovskaya; V I Golubev; I S Kulaev
Journal:  Dokl Biol Sci       Date:  2006 Sep-Oct

2.  Mycocin production in Pseudozyma tsukubaensis.

Authors:  Wladyslav I Golubev; Ilona Pfeiffer; Ellen W Golubeva
Journal:  Mycopathologia       Date:  2006-10       Impact factor: 2.574

3.  The transition from a phytopathogenic smut ancestor to an anamorphic biocontrol agent deciphered by comparative whole-genome analysis.

Authors:  François Lefebvre; David L Joly; Caroline Labbé; Beate Teichmann; Rob Linning; François Belzile; Guus Bakkeren; Richard R Bélanger
Journal:  Plant Cell       Date:  2013-06-25       Impact factor: 11.277

4.  Beta hydroxylation of glycolipids from Ustilago maydis and Pseudozyma flocculosa by an NADPH-dependent β-hydroxylase.

Authors:  Beate Teichmann; François Lefebvre; Caroline Labbé; Michael Bölker; Uwe Linne; Richard R Bélanger
Journal:  Appl Environ Microbiol       Date:  2011-09-16       Impact factor: 4.792

5.  Ecological basis of the interaction between Pseudozyma flocculosa and powdery mildew fungi.

Authors:  Walid Hammami; Candy Quiroga Castro; Wilfried Rémus-Borel; Caroline Labbé; Richard R Bélanger
Journal:  Appl Environ Microbiol       Date:  2010-11-29       Impact factor: 4.792

6.  Overview on Glycosylated Lipids Produced by Bacteria and Fungi: Rhamno-, Sophoro-, Mannosylerythritol and Cellobiose Lipids.

Authors:  Susanne Zibek; Gloria Soberón-Chávez
Journal:  Adv Biochem Eng Biotechnol       Date:  2022       Impact factor: 2.635

7.  Proteomic analysis of the metabolic adaptation of the biocontrol agent Pseudozyma flocculosa leading to glycolipid production.

Authors:  Walid Hammami; Florian Chain; Dominique Michaud; Richard R Bélanger
Journal:  Proteome Sci       Date:  2010-02-09       Impact factor: 2.480

8.  Production of antifungal cellobiose lipids by Trichosporon porosum.

Authors:  T V Kulakovskaya; W I Golubev; M A Tomashevskaya; E V Kulakovskaya; A S Shashkov; A A Grachev; A S Chizhov; N E Nifantiev
Journal:  Mycopathologia       Date:  2009-09-15       Impact factor: 2.574

Review 9.  Simple glycolipids of microbes: Chemistry, biological activity and metabolic engineering.

Authors:  Ahmad Mohammad Abdel-Mawgoud; Gregory Stephanopoulos
Journal:  Synth Syst Biotechnol       Date:  2017-12-15

10.  The antifungal effect of cellobiose lipid on the cells of Saccharomyces cerevisiae depends on carbon source.

Authors:  Ludmila V Trilisenko; Ekaterina V Kulakovskaya; Tatiana V Kulakovskaya; Alexander Yu Ivanov; Nikita V Penkov; Vladimir M Vagabov; Igor S Kulaev
Journal:  Springerplus       Date:  2012-09-25
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