Literature DB >> 15791307

Catalytic enantioselective conjugate addition of dialkylzinc reagents to N-substituted-2,3-dehydro-4-piperidones.

Radovan Sebesta1, Maria Gabriella Pizzuti, Arnold J Boersma, Adriaan J Minnaard, Ben L Feringa.   

Abstract

The first, highly enantioselective, copper/phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents to N-substituted 2,3-dehydro-4-piperidones is described.

Entities:  

Year:  2005        PMID： 15791307     DOI： 10.1039/b417727d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  Synthesis of 6- and 7-membered cyclic enaminones: scope and mechanism.

Authors:  Micah J Niphakis; Brandon J Turunen; Gunda I Georg
Journal:  J Org Chem       Date:  2010-10-15       Impact factor: 4.354

2.  Catalytic Allylic Oxidation of Cyclic Enamides and 3,4-Dihydro-2H-Pyrans by TBHP.

Authors:  Yang Yu; Ranad Humeidi; James R Alleyn; Michael P Doyle
Journal:  J Org Chem       Date:  2017-08-04       Impact factor: 4.354

3.  A Photochemical Two-Step Formal [5+2] Cycloaddition: A Condensation/Ring-Expansion Approach to Substituted Azepanes.

Authors:  Scott M Thullen; David M Rubush; Tomislav Rovis
Journal:  Synlett       Date:  2017-06-29       Impact factor: 2.454

4.  Rhodium(I)-Complexes Catalyzed 1,4-Conjugate Addition of Arylzinc Chlorides to N-Boc-4-pyridone.

Authors:  Fenghai Guo; Matthew A McGilvary; Malcolm C Jeffries; Briana N Graves; Shekinah A Graham; Yuelin Wu
Journal:  Molecules       Date:  2017-05-01       Impact factor: 4.411

5.  Highly Enantioselective Catalytic Addition of Grignard Reagents to N-Heterocyclic Acceptors.

Authors:  Yafei Guo; Syuzanna R Harutyunyan
Journal:  Angew Chem Int Ed Engl       Date:  2019-07-30       Impact factor: 15.336

6.  Synthesis of Aminoethyl-Substituted Piperidine Derivatives as σ1 Receptor Ligands with Antiproliferative Properties.

Authors:  Catharina Holtschulte; Frederik Börgel; Stefanie Westphälinger; Dirk Schepmann; Gianluca Civenni; Erik Laurini; Domenico Marson; Carlo V Catapano; Sabrina Pricl; Bernhard Wünsch
Journal:  ChemMedChem       Date:  2022-02-09       Impact factor: 3.540

7.  Enantioselective Catalytic Dearomative Addition of Grignard Reagents to 4-Methoxypyridinium Ions.

Authors:  Yafei Guo; Marta Castiñeira Reis; Johanan Kootstra; Syuzanna R Harutyunyan
Journal:  ACS Catal       Date:  2021-06-28       Impact factor: 13.084
  7 in total

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