Literature DB >> 15789130

Clinical trials are too often founded on poor quality pre-clinical research.

P M Rothwell1.   

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Year:  2005        PMID： 15789130     DOI： 10.1007/s00415-005-0803-2

Source DB:  PubMed          Journal:  J Neurol        ISSN： 0340-5354            Impact factor:   4.849


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  4 in total

Review 1.  Why do all drugs work in animals but none in stroke patients? 2. Neuroprotective therapy.

Authors:  J Grotta
Journal:  J Intern Med       Date:  1995-01       Impact factor: 8.989

Review 2.  Reliable assessment of the effects of treatment on mortality and major morbidity, I: clinical trials.

Authors:  R Collins; S MacMahon
Journal:  Lancet       Date:  2001-02-03       Impact factor: 79.321

Review 3.  Nimodipine in animal model experiments of focal cerebral ischemia: a systematic review.

Authors:  J Horn; R J de Haan; M Vermeulen; P G Luiten; M Limburg
Journal:  Stroke       Date:  2001-10       Impact factor: 7.914

4.  Pooling of animal experimental data reveals influence of study design and publication bias.

Authors:  Malcolm R Macleod; Tori O'Collins; David W Howells; Geoffrey A Donnan
Journal:  Stroke       Date:  2004-04-01       Impact factor: 7.914
  4 in total

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