Literature DB >> 15788427

Porous poly (DL-lactic acid) modified chitosan-gelatin scaffolds for tissue engineering.

Haifeng Liu1, Fanglian Yao, Yutao Zhou, Kangde Yao, Dongrui Mei, Lei Cui, Yilin Cao.   

Abstract

Chitosan-gelatin (Cs-Gel) scaffolds are modified with poly (DL-lactic acid) (PDLLA) dichloromethane solution of different concentrations (0.1, 0.5, and 1.0%) and immersed in water after the evaporation of the solvent. The swollen scaffolds are freeze dried. The concentration of PDLLA has significant effects on both the physicomechanical properties and the cytocompatibility. Data reveal that only the 0.1% concentration could increase the tensile strength fourfold in comparison with the pristine Cs-Gel scaffold, while maintaining the human fibroblast adhesion, migration, and proliferation just like the Cs-Gel scaffold.

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Year:  2005        PMID: 15788427     DOI: 10.1177/0885328205048590

Source DB:  PubMed          Journal:  J Biomater Appl        ISSN: 0885-3282            Impact factor:   2.646


  2 in total

1.  Comparative study on the role of gelatin, chitosan and their combination as tissue engineered scaffolds on healing and regeneration of critical sized bone defects: an in vivo study.

Authors:  Ahmad Oryan; Soodeh Alidadi; Amin Bigham-Sadegh; Ali Moshiri
Journal:  J Mater Sci Mater Med       Date:  2016-09-02       Impact factor: 3.896

Review 2.  Chitosan and Its Potential Use as a Scaffold for Tissue Engineering in Regenerative Medicine.

Authors:  Martin Rodríguez-Vázquez; Brenda Vega-Ruiz; Rodrigo Ramos-Zúñiga; Daniel Alexander Saldaña-Koppel; Luis Fernando Quiñones-Olvera
Journal:  Biomed Res Int       Date:  2015-10-04       Impact factor: 3.411

  2 in total

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