Literature DB >> 15787330

Urothelial carcinoma of the bladder with trophoblastic differentiation: a case report.

Burçin Tuna1, Kutsal Yörükoğlu, Uğur Mungan, Ziya Kirkali.   

Abstract

We report a case of a urothelial carcinoma with trophoblastic differentiation of the bladder that occured in a 23-year-old man. The patient presented with hematuria. Multiple papillary masses were resected transurethrally. Histopathologically, grade III urothelial cell carcinoma contained giant cells that were positive for human chorionic gonadotrophin (HCG), placental alkalen phosphatase, and human placental lactogen. HCG secreting tumors are reported to be highly aggressive. The patient is alive and well without evidence of recurrent disease or metastasis at 10 months from transurethral resection. To our knowledge, this case is the youngest patient in the literature so far.

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Year:  2004        PMID： 15787330     DOI： 10.1007/s11255-004-0859-4

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  15 in total

1.  Carcinoembryonic antigen and beta-human chorionic gonadotropin as serum markers for advanced urothelial malignancies.

Authors:  F Dexeus; C Logothetis; E Hossan; M L Samuels
Journal:  J Urol       Date:  1986-08       Impact factor: 7.450

2.  [Screening for transitional cell carcinoma of the bladder with trophoblastic differentiation in Upper Galilee].

Authors:  M Moldavsy; A Sazbon; N Kuchersky; H Turani
Journal:  Harefuah       Date:  1998-02-15

Review 3.  Primary choriocarcinoma of the urinary bladder. Report of a case with probable epithelial origin.

Authors:  J A Obe; N Rosen; L G Koss
Journal:  Cancer       Date:  1983-10-15       Impact factor: 6.860

Review 4.  Primary and metaplastic choriocarcinoma of the bladder. A report of two cases.

Authors:  S Yokoyama; Y Hayashida; J Nagahama; I Nakayama; K Kashima; J Ogata
Journal:  Acta Cytol       Date:  1992 Mar-Apr       Impact factor: 2.319

5.  Immunohistochemical demonstration of human chorionic gonadotropin in tumors of the urinary bladder.

Authors:  H T Yamase; R S Wurzel; P T Nieh; B Gondos
Journal:  Ann Clin Lab Sci       Date:  1985 Sep-Oct       Impact factor: 1.256

6.  Primary gastric choriocarcinoma: case report with review of world literature.

Authors:  K Jindrak; J F Bochetto; L I Alpert
Journal:  Hum Pathol       Date:  1976-09       Impact factor: 3.466

7.  Ectopic beta-human chorionic gonadotropin production by bladder urothelial neoplasia.

Authors:  V M Shah; J Newman; J Crocker; C R Chapple; M J Collard; J M O'Brien; J Considine
Journal:  Arch Pathol Lab Med       Date:  1986-02       Impact factor: 5.534

8.  Transitional cell carcinoma of the renal pelvis with choriocarcinomatous differentiation. Immunohistochemical and immunoelectron microscopic assessment of human chorionic gonadotropin production by transitional cell carcinoma of the urinary bladder.

Authors:  D Grammatico; D J Grignon; P Eberwein; R R Shepherd; S A Hearn; J C Walton
Journal:  Cancer       Date:  1993-03-01       Impact factor: 6.860

9.  Human chorionic gonadotrophin expression and histological findings as predictors of response to radiotherapy in carcinoma of the bladder.

Authors:  J E Martin; B J Jenkins; R J Zuk; R T Oliver; S I Baithun
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

10.  Ectopic production of human chorionic gonadotropin by poorly differentiated transitional cell tumors of the urinary tract.

Authors:  R S Wurzel; H T Yamase; P T Nieh
Journal:  J Urol       Date:  1987-03       Impact factor: 7.450
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  1 in total

1.  Urothelial carcinoma of the prostate with raised β-hCG levels: a case report.

Authors:  Julia Sołek; Marta Kalwas; Magdalena Sobczak; Sylwia Dębska-Szmich; Piotr Kupnicki; Dorota Jesionek-Kupnicka
Journal:  J Med Case Rep       Date:  2022-06-15
  1 in total

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