Literature DB >> 15786469

Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD.

Angela Pyle1, Thomas Foltynie, Watcharee Tiangyou, Claire Lambert, Sharon M Keers, Liesl M Allcock, Jill Davison, Simon J Lewis, Robert H Perry, Roger Barker, David J Burn, Patrick F Chinnery.   

Abstract

There is increasing evidence that genetic variants of mitochondrial DNA have an important role in the cause of idiopathic Parkinson's disease. We determined the mitochondrial DNA haplogroup of 455 Parkinson's disease cases, 185 Alzheimer's disease cases, and 447 healthy English control subjects. The UKJT haplogroup cluster was associated with a 22% reduction in population-attributable risk for Parkinson's disease. There was no association between individual haplogroups or the UKJT cluster and Alzheimer's disease, confirming that the association with Parkinson's disease was disease specific and not a general effect seen in all neurodegenerative diseases.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15786469     DOI： 10.1002/ana.20417

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  73 in total

Review 1.  Recent advances in the genetics of Parkinson's disease.

Authors:  Ian Martin; Valina L Dawson; Ted M Dawson
Journal:  Annu Rev Genomics Hum Genet       Date:  2011       Impact factor: 8.929

2.  Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry.

Authors:  David M Krzywanski; Douglas R Moellering; David G Westbrook; Kimberly J Dunham-Snary; Jamelle Brown; Alexander W Bray; Kyle P Feeley; Melissa J Sammy; Matthew R Smith; Theodore G Schurr; Joseph A Vita; Namasivayam Ambalavanan; David Calhoun; Louis Dell'Italia; Scott W Ballinger
Journal:  Circ Cardiovasc Genet       Date:  2016-01-19

3.  Mitochondrial DNA haplogroups and amyotrophic lateral sclerosis.

Authors:  Patrick F Chinnery; Catherine Mowbray; Hannah Elliot; Joanna L Elson; Hannah Nixon; Judith Hartley; Pamela J Shaw
Journal:  Neurogenetics       Date:  2006-11-03       Impact factor: 2.660

Review 4.  The unresolved role of mitochondrial DNA in Parkinson's disease: An overview of published studies, their limitations, and future prospects.

Authors:  Amica C Müller-Nedebock; Rebecca R Brennan; Marianne Venter; Ilse S Pienaar; Francois H van der Westhuizen; Joanna L Elson; Owen A Ross; Soraya Bardien
Journal:  Neurochem Int       Date:  2019-06-21       Impact factor: 3.921

5.  Mitochondrial DNA haplogroups and mutations in children with acquired central demyelination.

Authors:  S Venkateswaran; K Zheng; M Sacchetti; D Gagne; D L Arnold; A D Sadovnick; S W Scherer; B Banwell; A Bar-Or; D K Simon
Journal:  Neurology       Date:  2011-02-02       Impact factor: 9.910

6.  The power to detect disease associations with mitochondrial DNA haplogroups.

Authors:  David C Samuels; Andrew D Carothers; Robin Horton; Patrick F Chinnery
Journal:  Am J Hum Genet       Date:  2006-02-17       Impact factor: 11.025

Review 7.  Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis.

Authors:  Rebecca Banerjee; Anatoly A Starkov; M Flint Beal; Bobby Thomas
Journal:  Biochim Biophys Acta       Date:  2008-11-14

8.  MANF improves the MPP+/MPTP-induced Parkinson's disease via improvement of mitochondrial function and inhibition of oxidative stress.

Authors:  Yigang Liu; Jingxing Zhang; Ming Jiang; Qiong Cai; Jianmin Fang; Lingjing Jin
Journal:  Am J Transl Res       Date:  2018-05-15       Impact factor: 4.060

9.  Mitochondrial DNA haplogroups and subhaplogroups are associated with Parkinson's disease risk in a Polish PD cohort.

Authors:  Katarzyna Gaweda-Walerych; Aleksandra Maruszak; Krzysztof Safranow; Monika Bialecka; Gabriela Klodowska-Duda; Krzysztof Czyzewski; Jaroslaw Slawek; Monika Rudzinska; Maria Styczynska; Grzegorz Opala; Marek Drozdzik; Jeffrey A Canter; Maria Barcikowska; Cezary Zekanowski
Journal:  J Neural Transm (Vienna)       Date:  2008-09-23       Impact factor: 3.575

10.  Mitochondrial DNA polymorphisms and haplogroups in Parkinson's disease and control individuals with a similar genetic background.

Authors:  Helen Latsoudis; Cleanthe Spanaki; Grigoris Chlouverakis; Andreas Plaitakis
Journal:  J Hum Genet       Date:  2008-02-20       Impact factor: 3.172
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.