Literature DB >> 15785803

On the origin of the DNA sequence selectivity of the azinomycins.

Rachel C LePla1, Cyrille A S Landreau, Michael Shipman, George D D Jones.   

Abstract

Simplified synthetic azinomycins preferentially induce in vitro DNA interstrand cross-links at the same 5'-d(GCC)-3' site as the natural products revealing that non-covalent interactions are relatively unimportant in defining sequence specificity.

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Year:  2005        PMID： 15785803     DOI： 10.1039/b502188j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Sequence selectivity of azinomycin B in DNA alkylation and cross-linking: a QM/MM study.

Authors:  Dhurairajan Senthilnathan; Anbarasan Kalaiselvan; Ponnambalam Venuvanalingam
Journal:  J Mol Model       Date:  2012-08-24       Impact factor: 1.810

2.  Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.

Authors:  Yinggang Luo; Shuangjun Lin; Jian Zhang; Heather A Cooke; Steven D Bruner; Ben Shen
Journal:  J Biol Chem       Date:  2008-04-03       Impact factor: 5.157

3.  Identification of a novel structure-specific endonuclease AziN that contributes to the repair of azinomycin B-mediated DNA interstrand crosslinks.

Authors:  Xiaorong Chen; Yuedi Sun; Shan Wang; Kun Ying; Le Xiao; Kai Liu; Xiuli Zuo; Jing He
Journal:  Nucleic Acids Res       Date:  2020-01-24       Impact factor: 16.971

4.  Characterization of a novel DNA glycosylase from S. sahachiroi involved in the reduction and repair of azinomycin B induced DNA damage.

Authors:  Shan Wang; Kai Liu; Le Xiao; LiYuan Yang; Hong Li; FeiXue Zhang; Lei Lei; ShengQing Li; Xu Feng; AiYing Li; Jing He
Journal:  Nucleic Acids Res       Date:  2015-09-22       Impact factor: 16.971
  4 in total

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